Adrian V. Lee

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Dual HER2/HER3 Targeting with Antibody-Drug Conjugates Reveals a Novel Therapeutic Strategy for HER2-Mutant Lobular Breast Cancer

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-06-19

• Correlation of Ki-67 with tumor fraction in metastatic HR-positive invasive lobular and no special type breast cancer.

  Journal of Clinical Oncology · 2026-05-28

• Organ- and histology-specific molecular and immune landscape of metastatic breast cancer.

  Journal of Clinical Oncology · 2026-05-27

• Whole-genome doubling drives immune evasion by silencing antigen presentation

  Cancer Cell · 2026-05-01 · 1 citations

• Quantitative and qualitative patient-reported analysis of misdiagnosis and/or late diagnosis of metastatic lobular cancer

  medRxiv · 2026-04-20

• Identification of cycling regulatory T cell precursors as conductors of immune escape during breast carcinoma progression

  Cancer Cell · 2026-04-16 · 1 citations

• Benchmarking scRNA-seq Copy Number Inference: A Comprehensive Evaluation and Practitioner’s Guide

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-04-15

• Abstract 7392: A cancer cell-intrinsic PAR1/MALT1/PD-L1 signaling pathway drives immune evasion in triple-negative breast cancer

  Cancer Research · 2026-04-03

• Abstract 2824: Intragenic rearrangement burden: A novel biomarker to predict immune checkpoint blockade response in TMB-low cancers

  Cancer Research · 2026-04-03

• Identification and credentialing of patient-derived xenograft models of invasive lobular carcinoma

  Disease Models & Mechanisms · 2026-04-01

• Use of ctDNA in Older Women with ER+ Breast Cancer to Facilitate Surgical De-escalation: A Prospective, Hybrid-Decentralized Trial with Correlative Studies

  Clinical Cancer Research · 2026-03-19 · 1 citations

• Estrogen receptor-positive cell line xenograft models recapitulate metastatic dissemination and endocrine response of invasive lobular breast carcinoma

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-03-18 · 1 citations

• Saturating hepatic clearance drives elevated cfDNA and fragment shortening in cancer

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-03-06

• Clinical and histopathological characterization of metastatic lobular breast cancer: lessons learned from post-mortem tissue donation programs

  npj Breast Cancer · 2026-02-20

• The ADAPT learning cancer treatment system: ARPA-H’s initiative to revolutionize cancer therapy

  Cancer Cell · 2026-01-08 · 1 citations

• Correction: ADAM22/LGI1 complex as a new actionable target for breast cancer brain metastasis

  BMC Medicine · 2025-12-13

• Supplementary Figures S1-S10 from p38MAPKα Stromal Reprogramming Sensitizes Metastatic Breast Cancer to Immunotherapy

  2025-12-11

• Supplementary Table S1 from p38MAPKα Stromal Reprogramming Sensitizes Metastatic Breast Cancer to Immunotherapy

  2025-12-11

• Supplementary Figure S1 from SWI/SNF Functions as a Gatekeeper of Enhancer Chromatin Access to Control Progression of Mesenchymal Triple-Negative Breast Cancer

  2025-12-01

• Supplementary Table S2 from SWI/SNF Functions as a Gatekeeper of Enhancer Chromatin Access to Control Progression of Mesenchymal Triple-Negative Breast Cancer

  2025-12-01