Alex Aliper

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Cover Feature: An Internal Sulfur–Lone Pair Interaction Enabled the Discovery of Potent and Sub‐Family Selective PKMYT1 Inhibitors (ChemMedChem 6/2026)

  ChemMedChem · 2026-03-27

• An Internal Sulfur–Lone Pair Interaction Enabled the Discovery of Potent and Sub‐Family Selective PKMYT1 Inhibitors

  ChemMedChem · 2026-03-26 · 1 citations

• Discovery of a bifunctional PKMYT1-targeting PROTAC empowered by AI-generation

  Nature Communications · 2025-11-28 · 14 citations

• <scp>AlphaFold</scp> Kinase Optimizer: Enhancing Virtual Screening Performance Through Automated Refinement of <scp>AlphaFold</scp> ‐Based Kinase Structures

  Proteins Structure Function and Bioinformatics · 2025-09-16 · 1 citations

• Author response for "AlphaFold Kinase Optimizer: Enhancing Virtual Screening Performance Through Automated Refinement of AlphaFold-Based Kinase Structures"

  2025-08-15

• Advancing Target Discovery Through Disease-Specific Integration of Multi-Modal Target Identification Models and Comprehensive Target Benchmarking SystemPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-08-08

• Variability in radiotherapy outcomes across cancer types: a comparative study of glioblastoma multiforme and low-grade gliomas

  Aging · 2025-02-27 · 1 citations

• Quantum-computing-enhanced algorithm unveils potential KRAS inhibitors

  Nature Biotechnology · 2025-01-22 · 57 citations

• A Standardized Protocol for Mouse Longevity Studies in Preclinical Drug Development

  Aging and Disease · 2025-01-01 · 3 citations

• Generative Drug Discovery

  2024-12-24 · 1 citations

• AttenhERG: a reliable and interpretable graph neural network framework for predicting hERG channel blockers

  Journal of Cheminformatics · 2024-12-23 · 15 citations

• Discovery of pyrrolopyrimidinone derivatives as potent PKMYT1 inhibitors for the treatment of cancer

  European Journal of Medicinal Chemistry · 2024-11-05 · 13 citations

• Discovery of 1(2H)-phthalazinone and 1(2H)-isoquinolinone derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors

  European Journal of Medicinal Chemistry · 2024-09-16 · 9 citations

• Precious2GPT: the combination of multiomics pretrained transformer and conditional diffusion for artificial multi-omics multi-species multi-tissue sample generation

  npj Aging · 2024-08-08 · 23 citations

• Precious3GPT: Multimodal Multi-Species Multi-Omics Multi-Tissue Transformer for Aging Research and Drug DiscoveryPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2024-07-25 · 16 citations

• Variability in Radiotherapy Outcomes Across Cancer Types: A Comparative Study of Glioblastoma Multiforme and Low-Grade GliomasPreprint

  medRxiv · 2024-07-05 · 2 citations