Andrew A. Pieper

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Biliverdin reductase A is a major determinant of protective NRF2 signaling

  Proceedings of the National Academy of Sciences · 2025-09-30 · 5 citations

• Systematic characterization of cell type-specific master metabolic regulators in Alzheimer's diseasePreprint

  Research Square · 2025-08-18

• Cell type-specific master metabolic regulators of Alzheimer’s diseasePreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-07-17 · 1 citations

• A Scalable Human Brain Cell Atlas Foundation Model Dissects the Cellular Immune Codes and Cognitive ResiliencePreprint

  Research Square · 2025-07-08

• Comprehensive characterization of the RNA editing landscape in the human aging brains with Alzheimer's disease

  Alzheimer s & Dementia · 2025-07-01 · 6 citations

• Erratum to ‘Utilization of precision medicine digital twins for drug discovery in Alzheimer's disease’, Neurotherapeutics, 22(3), e00553

  Neurotherapeutics · 2025-06-19

• Combining xQTL and genome-wide association studies from ethnically diverse populations improves druggable gene discoveryPreprint

  Research Square · 2025-05-28 · 1 citations

• Genomic and epigenomic insights into purkinje and granule neurons in Alzheimer’s disease and related dementia using single-nucleus multiome analysisPreprint

  Research Square · 2025-04-01 · 3 citations

• Efficacy and safety of passive immunotherapies targeting amyloid beta in Alzheimer’s disease: A systematic review and meta-analysis

  PLoS Medicine · 2025-03-31 · 20 citations

• A network-based systems genetics framework identifies pathobiology and drug repurposing in Parkinson’s disease

  npj Parkinson s Disease · 2025-01-21 · 10 citations

• Single-cell digital twins identify drug targets and repurposable medicine in Alzheimer’s diseasePreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-01-20 · 2 citations

• Combining genetics with real-world patient data enables ancestry-specific target identification and drug discovery in Alzheimer’s diseasePreprint

  Research Square · 2025-01-15 · 3 citations

• Combining xQTL and Genome-Wide Association Studies from Ethnically Diverse Populations Improves Druggable Gene DiscoveryPreprint

  SSRN Electronic Journal · 2025-01-01 · 1 citations

• Critical Evaluation of Real-World Evidence for Repurposable Medicines in the Alzheimer's Disease Drug Development Pipeline Using a Target Trial EmulationPreprint

  SSRN Electronic Journal · 2025-01-01

• Single‐microglia transcriptomic transition network‐based prediction and real‐world patient data validation identifies ketorolac as a repurposable drug for Alzheimer's disease

  Alzheimer s & Dementia · 2024-12-06 · 13 citations

• Deterioration of neuronal primary cilia in Alzheimer’s disease

  Alzheimer s & Dementia · 2024-12-01 · 3 citations

• Alzheimer’s disease genetics and real‐world patient data fuel target and drug discovery in European and African American Ancestries using AI/ML approaches

  Alzheimer s & Dementia · 2024-12-01 · 1 citations

• Single‐Microglia Transcriptomic Transition Network‐based Prediction and Real‐world Patient Data Validation Identifies Ketorolac as a Repurposable Drug for Alzheimer’s Disease

  Alzheimer s & Dementia · 2024-12-01

• Sildenafil is a candidate drug for Alzheimer’s disease: Real‐world patient data observation and functional validation in patient iPSC‐derived neurons and the 5xFAD mouse model

  Alzheimer s & Dementia · 2024-12-01

• Cross‐species protein interactome network‐based analysis of GWAS and human brain quantitative trait loci (x‐QTL) data identifies risk genes and drug targets for Alzheimer’s disease

  Alzheimer s & Dementia · 2024-12-01