Ayellet V. Segrè

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• A Primary Open-Angle Glaucoma Locus Near Transcription Factor PRRX1 Identified in the Million Veteran Program

  Ophthalmology Science · 2026-04-17

• Genome-Wide Association Study for Glucocorticoid-Induced Ocular Hypertension

  medRxiv · 2026-01-02

• Time-dependent Glucocorticoid-Induced Transcriptomic Changes in Human Trabecular Meshwork and Schlemm’s Canal

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-01-01

• Dual-Level Pattern Tree for Visual Field Improves Glaucoma Progression and Polygenic Risk Prediction

  Translational Vision Science & Technology · 2025-12-04

• REECAP: Contrastive learning of retinal aging reveals genetic loci linking morphology to eye diseasePreprint

  medRxiv · 2025-11-20 · 1 citations

• Deep-learning-derived glaucoma-related endophenotypes enable novel genome-wide genetic and functional discoveryPreprint

  medRxiv · 2025-11-06 · 2 citations

• Recall by polygenic risk score in two biobanks supports a genomic approach for glaucoma detectionPreprint

  Research Square · 2025-08-05 · 1 citations

• Polygenic Risk Prediction for Normal-Tension Glaucoma

  Investigative Ophthalmology & Visual Science · 2025-07-01 · 2 citations

• Paired DNA and RNA sequencing uncovers common and rare genetic variants regulating gene expression in the human retinaPreprint

  medRxiv · 2025-04-26

• Author response: Pyruvate and related energetic metabolites modulate resilience against high genetic risk for glaucoma

  2025-04-24 · 1 citations

• Pyruvate and related energetic metabolites modulate resilience against high genetic risk for glaucoma

  eLife · 2025-04-24

• Genetic Risk for Open-Angle Glaucoma Subtypes Is Associated with Specific Visual Field Defect Classes

  Ophthalmology · 2025-04-11 · 1 citations

• Author response: Pyruvate and Related Energetic Metabolites Modulate Resilience Against High Genetic Risk for Glaucoma

  2025-03-28

• Pyruvate and Related Energetic Metabolites Modulate Resilience Against High Genetic Risk for GlaucomaPreprint

  eLife · 2025-03-28

• Pyruvate and Related Energetic Metabolites Modulate Resilience Against High Genetic Risk for GlaucomaPreprint

  eLife · 2025-03-10

• Pyruvate and related energetic metabolites modulate resilience against high genetic risk for glaucoma

  eLife · 2025-03-10 · 8 citations

• Does Age Modify the Relation Between Genetic Predisposition to Glaucoma and Various Glaucoma Traits in the UK Biobank?

  Investigative Ophthalmology & Visual Science · 2025-02-21 · 3 citations

• Integrative analysis of single-cell transcriptomics and genetic associations identify cell states associated with vascular disease

  Atherosclerosis · 2025-02-03 · 3 citations

• Pyruvate and Related Energetic Metabolites Modulate Resilience Against High Genetic Risk for GlaucomaPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-01-22

• Genome-wide meta-analysis identifies 22 loci for normal tension glaucoma with significant overlap with high tension glaucoma

  Nature Communications · 2024-11-17 · 13 citations