Belinda Giardine

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Functional impact of genetic background on variable expressivity in neurodevelopmental disorders

  Nature Communications · 2026-05-01

• Abstract 7237: LDB1-dependent enhancer connectivity constrains a metabolic synthetic lethality in T-cell acute lymphoblastic leukemia

  Cancer Research · 2026-04-03

• An optimized CRISPR-Cas12a genome-wide screen reveals PTPA phosphatase pathway in fetal hemoglobin silencing

  Blood · 2026-01-12 · 1 citations

• Gene expression analysis and proximity labeling reveal post-transcriptional functions of the yeast RNA polymerase II regulator Def1

  Journal of Biological Chemistry · 2025-12-05 · 1 citations

• Highly discriminative globin gene activation by the noncanonical BAF chromatin remodeling complex

  Blood · 2025-11-14 · 1 citations

• LDB1-dependent enhancer networks drive high-risk transcriptional programs in T-cell acute lymphoblastic leukemia

  Blood · 2025-11-03

• Auxin-induced depletion of human CCR4-NOT subunits reveals opposing functions of CNOT1 and CNOT4 in mRNA metabolism

  Journal of Biological Chemistry · 2025-10-28 · 6 citations

• Transcriptome and chromatin accessibility divergence during differentiation of a bipotential progenitor cell population to erythroblasts and megakaryocytes

  Journal of Biological Chemistry · 2025-10-15

• Single-stranded DNA-binding proteins are essential components of the architectural LDB1 protein complex

  Molecular Cell · 2025-08-01 · 2 citations

• An integrated framework for functional dissection of variable expressivity in genetic disordersPreprint

  medRxiv · 2025-07-23 · 2 citations

• Divergence between transcriptomes and chromatin accessibility during differentiation from a bipotential progenitor cell population to erythroblasts and megakaryocytesPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-07-03

• Single-stranded DNA binding proteins are essential components of the architectural LDB1 protein complexPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-06-06 · 1 citations

• LDB1 establishes multi-enhancer networks to regulate gene expression

  Molecular Cell · 2024-12-24 · 51 citations

• LDB1 Establishes Multi-Enhancer Networks to Regulate Erythroid Gene Expression

  Blood · 2024-11-05

• Defining Oncogenic Transcriptional Networks Regulated By LDB1 in T-Cell Acute Lymphoblastic Leukemia

  Blood · 2024-11-05

• Human CCR4-NOT globally regulates gene expression and is a novel silencer of retrotransposon activationPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2024-09-10 · 2 citations

• YY1-controlled regulatory connectivity and transcription are influenced by the cell cycle

  Nature Genetics · 2024-08-29 · 44 citations

• LDB1 establishes multi-enhancer networks to regulate gene expressionPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2024-08-24 · 10 citations