Full Professor(heuristic)

Alzheimer's disease research and treatments · Physiology

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h-index94
i10-index294
Publications593
Citations50,449

Grants

27 total · 21 active

NIH #R01AG074010

Dissect the interplay between sex and APOE at the single cell level to uncover novel pathways, targets and therapeutics for Alzheimer's disease

Expiring Soon
Amount
$1M–$2M
Period
2021-09-30 → 2026-08-31
PIs
2

NIH #R01CA224275

Lipid Unsaturation Drives Ovarian Cancer Progression

Active
Amount
$600K–$700K
Period
2018-08-01 → 2031-05-31
PIs
3

Awarded at METHODIST HOSPITAL RESEARCH INSTITUTE

NIH #R01AG095513

Examining Unique Markers and Risk Factors for AD/ADRD in Foreign- and Native-born Older Chinese Americans: A Study of Social Determinants of Health, Sleep Patterns, Neuroimaging, and Plasma Biomarkers

Active
Amount
$4M–$5M
Period
2025-09-15 → 2030-08-31
PIs
4

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All Grants

27 total · 21 active

NIH #R01AG074010

Dissect the interplay between sex and APOE at the single cell level to uncover novel pathways, targets and therapeutics for Alzheimer's disease

Expiring Soon
Amount
$1M–$2M
Period
2021-09-30 → 2026-08-31
PIs
2

NIH #R01CA224275

Lipid Unsaturation Drives Ovarian Cancer Progression

Active
Amount
$600K–$700K
Period
2018-08-01 → 2031-05-31
PIs
3

Awarded at METHODIST HOSPITAL RESEARCH INSTITUTE

NIH #R01AG095513

Examining Unique Markers and Risk Factors for AD/ADRD in Foreign- and Native-born Older Chinese Americans: A Study of Social Determinants of Health, Sleep Patterns, Neuroimaging, and Plasma Biomarkers

Active
Amount
$4M–$5M
Period
2025-09-15 → 2030-08-31
PIs
4

NIH #R01NS145483

Structural Studies and Drug Discovery to Interrogate the Function of Neuronal SLC4 Transporters

Active
Amount
$600K–$700K
Period
2025-07-01 → 2030-06-30
PIs
3

NIH #R01GM163112

Cost-effective workflow for efficient unsaturated lipidomics enabled by a novel ion chemistry

Active
Amount
$1M–$2M
Period
2026-04-01 → 2030-03-31
PIs
1

Awarded at UNIVERSITY OF NORTH CAROLINA GREENSBORO

NIH #R01AG085182

Identification and Characterization of Senescent Cells in Molecular Subtypes of Alzheimer's Disease

Active
Amount
$800K–$900K
Period
2024-09-15 → 2029-06-30
PIs
2

NIH #R35GM133580

Probing and Perturbing Transcriptional Condensates with Multiscale Modeling and Deep Learning

Active
Amount
$400K–$500K
Period
2019-08-01 → 2029-05-31
PIs
1

Awarded at MASSACHUSETTS INSTITUTE OF TECHNOLOGY

NIH #U01AG088351

Age related loss of immune resilience during response to severe respiratory viral infections

Active
Amount
$500K–$600K
Period
2024-07-01 → 2029-04-30
PIs
3

Awarded at NEW YORK UNIVERSITY SCHOOL OF MEDICINE

NIH #R01CA290743

Sustaining antitumor effector CD8+ T cells for cancer therapy

Active
Amount
$600K–$700K
Period
2024-05-17 → 2029-04-30
PIs
2

Awarded at NORTHWESTERN UNIVERSITY

NIH #R01CA290780

Metabolic regulation of immunosuppressive myeloid cells in the tumor microenvironment of pancreatic cancer.

Active
Amount
$600K–$700K
Period
2024-04-02 → 2029-03-31
PIs
2

Awarded at UNIVERSITY OF MICHIGAN AT ANN ARBOR

NIH #R01CA286160

Targeting Immune Escape in CML/MPN Transformation

Active
Amount
$500K–$600K
Period
2023-12-08 → 2028-11-30
PIs
2

Awarded at BECKMAN RESEARCH INSTITUTE/CITY OF HOPE

NIH #UH3AG083258

Research Infrastructure for the study of Alzheimer's Disease and Alzheimer's Disease-related dementias in older Asian Americans

Active
Amount
$1M–$2M
Period
2023-09-15 → 2028-08-31
PIs
4

NIH #U01CA299401

Advancing Protein Isoform Analysis through an Integrated Computational Framework.

Active
Amount
$300K–$400K
Period
2025-08-01 → 2028-07-31
PIs
2

Awarded at BAYLOR COLLEGE OF MEDICINE

NIH #R01HL169427

Developing hemophilia A therapeutics by targeting translational and posttranslational regulation of FVIII

Active
Amount
$500K–$600K
Period
2024-03-15 → 2028-01-31
PIs
1

Awarded at CLEVELAND CLINIC LERNER COM-CWRU

NSF #2541725

EAGER: Multimodal AI for Elucidating Genome Structure-Function Relationships in Human Brain Cells

Active
Amount
$300K–$400K
Period
2025-08-15 → 2027-07-31
PIs
1

Awarded at Massachusetts Institute of Technology

NIH #F99CA305515

From T Cells to Dendritic Cells: Mechanistic Dissection of CTLA4 and TIM3 in Cancer Immunity

Active
Amount
<$100K
Period
2025-08-01 → 2027-07-31
PIs
1

Awarded at UNIVERSITY OF CALIFORNIA, SAN DIEGO

NIH #U24CA271076

iPGDAC, An Integrative Proteogenomic Data Analysis Center for CPTAC

Active
Amount
$800K–$900K
Period
2022-06-01 → 2027-05-31
PIs
1

Awarded at BAYLOR COLLEGE OF MEDICINE

NIH #R01CA258857

Targeting posttranslational modifications of CD73 in TNBCs

Active
Amount
$600K–$700K
Period
2021-11-09 → 2027-03-31
PIs
2

Awarded at EMORY UNIVERSITY

NIH #R01CA257926

Innovative Research for Cancer Nanotechnology (IRCN) for Enhancing Melanoma-specific Immune Responses by the Rational Design of Spherical Nucleic Acids

Active
Amount
$500K–$600K
Period
2022-03-14 → 2027-02-28
PIs
2

Awarded at NORTHWESTERN UNIVERSITY

NIH #R01CA257520

A deubiquitination module controls Treg adaptation to tumor microenvironment

Active
Amount
$500K–$600K
Period
2021-01-01 → 2026-12-31
PIs
2

Awarded at NORTHWESTERN UNIVERSITY

NIH #R01CA258981

The Role of miR-142 in the Transformation of Clonal Hematopoietic Disorders into AML

Active
Amount
$500K–$600K
Period
2022-01-01 → 2026-12-31
PIs
2

Awarded at BECKMAN RESEARCH INSTITUTE/CITY OF HOPE

NIH #R01CA250101

The distinct role of cysteinyl leukotriene receptor for myeloid-derived suppressive cells

Amount
$500K–$600K
Period
2020-05-15 → 2026-04-30
PIs
1

Awarded at NORTHWESTERN UNIVERSITY

NSF #2042362

CAREER: Chromatin Folding from the Bottom-up

Amount
$1M–$2M
Period
2021-02-01 → 2026-01-31
PIs
1

Awarded at Massachusetts Institute of Technology

NSF #1715859

Breaking the Histone Code: Predicting Genome Organization with Chromatin States

Amount
$600K–$700K
Period
2017-08-01 → 2020-07-31
PIs
1

Awarded at Massachusetts Institute of Technology

NSF #0970104

RUI: Understanding Quark-Gluon Plasma Properties Via Parton Transport

Amount
$100K–$200K
Period
2010-07-15 → 2014-06-30
PIs
1

Awarded at Arkansas State University Main Campus

NSF #0554930

RUI: Dynamical aspects of Quark-Gluon Plasma production

Amount
$100K–$200K
Period
2006-07-01 → 2011-06-30
PIs
1

Awarded at Arkansas State University Main Campus

NSF #0140046

Dynamics of ultradense matter produced in relativistic nuclear collisions

Amount
<$100K
Period
2002-08-01 → 2006-07-31
PIs
1

Awarded at Arkansas State University Main Campus

Recent Public Signals

  1. New paper: MetaCell-based Multiscale Network Analysis (MCMNA) (Zenodo (CERN European Organization for Nuclear Research))2026-06-26
  2. New NIH award: Cost-effective workflow for efficient unsaturated lipidomics enabled by a novel ion chemistry2026-04-01
  3. New NIH award: Examining Unique Markers and Risk Factors for AD/ADRD in Foreign- and Native-born Older Chinese Americans: A Study of Social Determinants of Health, Sleep Patterns, Neuroimaging, and Plasma Biomarkers2025-09-15

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Data Freshness

  • Publications as of 2026-07-09
  • Grants as of 2026-08-30

Data may not be current

Find elsewhere

Institution / lab homepage Search on ResearchGate

ORCID: 0000-0002-9549-5653

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