Full Professor(heuristic)

Genomics and Chromatin Dynamics · Molecular Biology

h-index131
i10-index296
Publications536
Citations112,644

Grants

34 total · 15 active

NIH #1U54AG079758-01

Spatial mapping senescent cells across the mouse lifespan by multiplex transcriptomics and epigenomics

Expiring Soon
Amount
$2.6M
Period
2022-08-01 → 2026-07-31
PIs
2
Est. capacity / PI
~0 students

Awarded at SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE

NIH #5U54AG079758-02

Spatial mapping senescent cells across the mouse lifespan by multiplex transcriptomics and epigenomics

Expiring Soon
Amount
$2.7M
Period
2022-08-01 → 2026-07-31
PIs
2
Est. capacity / PI
~0 students

Awarded at SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE

NIH #5U54AG079758-03

Spatial mapping senescent cells across the mouse lifespan by multiplex transcriptomics and epigenomics

Expiring Soon
Amount
$2.7M
Period
2022-08-01 → 2026-07-31
PIs
2
Est. capacity / PI
~0 students

Awarded at SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE

Student capacity is a rough estimate from remaining award size, split equally among PIs. Actual funding decisions vary.

All Grants

34 total · 15 active

NIH #1U54AG079758-01

Spatial mapping senescent cells across the mouse lifespan by multiplex transcriptomics and epigenomics

Expiring Soon
Amount
$2.6M
Period
2022-08-01 → 2026-07-31
PIs
2
Est. capacity / PI
~0 students

Awarded at SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE

NIH #5U54AG079758-02

Spatial mapping senescent cells across the mouse lifespan by multiplex transcriptomics and epigenomics

Expiring Soon
Amount
$2.7M
Period
2022-08-01 → 2026-07-31
PIs
2
Est. capacity / PI
~0 students

Awarded at SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE

NIH #5U54AG079758-03

Spatial mapping senescent cells across the mouse lifespan by multiplex transcriptomics and epigenomics

Expiring Soon
Amount
$2.7M
Period
2022-08-01 → 2026-07-31
PIs
2
Est. capacity / PI
~0 students

Awarded at SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE

NIH #5R01AG082127-04

Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regions

Active
Amount
$2.0M
Period
2023-06-01 → 2028-02-29
PIs
3
Est. capacity / PI
~3 students

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NIH #5R01AG082127-03

Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regions

Active
Amount
$2.0M
Period
2023-06-01 → 2028-02-29
PIs
3
Est. capacity / PI
~3 students

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NIH #5R01AG082127-02

Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regions

Active
Amount
$2.0M
Period
2023-06-01 → 2028-02-29
PIs
3
Est. capacity / PI
~3 students

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NIH #1R01AG082127-01

Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regions

Active
Amount
$2.1M
Period
2023-06-01 → 2028-02-29
PIs
3
Est. capacity / PI
~4 students

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NSF #2403088

Collaborative Research: OAC Core: CropDL - Scheduling and Checkpoint/Restart Support for Deep Learning Applications on HPC Clusters

Active
Amount
$225K
Period
2024-10-01 → 2027-09-30
PIs
1
Est. capacity / PI
~1 students

Awarded at College of William and Mary

NIH #3U54AG079758-04S1

Spatial Mapping Senescent Cells Across the Mouse Lifespan by Multiplex Transcriptomics and Epigenomics

Active
Amount
$199K
Period
2022-08-01 → 2027-07-31
PIs
2
Est. capacity / PI
~0 students

Awarded at SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE

NIH #5U54AG079758-04

Spatial mapping senescent cells across the mouse lifespan by multiplex transcriptomics and epigenomics

Active
Amount
$2.7M
Period
2022-08-01 → 2027-07-31
PIs
2
Est. capacity / PI
~4 students

Awarded at SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE

NIH #5UM1MH130994-04

Center for Multiomic Human Brain Cell Atlas

Active
Amount
$17.6M
Period
2022-09-01 → 2027-06-30
PIs
5
Est. capacity / PI
~12 students

Awarded at SALK INSTITUTE FOR BIOLOGICAL STUDIES

NIH #5UM1MH130994-03

Center for Multiomic Human Brain Cell Atlas

Active
Amount
$17.7M
Period
2022-09-01 → 2027-06-30
PIs
5
Est. capacity / PI
~12 students

Awarded at SALK INSTITUTE FOR BIOLOGICAL STUDIES

NIH #5UM1MH130994-02

Center for Multiomic Human Brain Cell Atlas

Active
Amount
$14.1M
Period
2022-09-01 → 2027-06-30
PIs
5
Est. capacity / PI
~9 students

Awarded at SALK INSTITUTE FOR BIOLOGICAL STUDIES

NIH #1UM1MH130994-01

Center for Multiomic Human Brain Cell Atlas

Active
Amount
$25.3M
Period
2022-09-01 → 2027-06-30
PIs
5
Est. capacity / PI
~17 students

Awarded at SALK INSTITUTE FOR BIOLOGICAL STUDIES

NIH #5U01HG012059-05

The impact of genomic variation on environment-induced changes in pancreatic beta cell states

Active
Amount
$1.3M
Period
2021-09-07 → 2027-05-31
PIs
4
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF CALIFORNIA, SAN DIEGO

NIH #5U01HG012059-04

The impact of genomic variation on environment-induced changes in pancreatic beta cell states

Amount
$1.3M
Period
2021-09-07 → 2026-05-31
PIs
4
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF CALIFORNIA, SAN DIEGO

NIH #5R01EY031663-03

Unraveling the molecular pathology of retinal degeneration through single cell genomics

Amount
$687K
Period
2021-06-01 → 2026-05-31
PIs
3
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF CALIFORNIA, SAN DIEGO

NIH #5U01HG012059-03

The impact of genomic variation on environment-induced changes in pancreatic beta cell states

Amount
$1.3M
Period
2021-09-07 → 2026-05-31
PIs
4
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF CALIFORNIA, SAN DIEGO

NIH #5R01EY031663-02

Unraveling the molecular pathology of retinal degeneration through single cell genomics

Amount
$647K
Period
2021-06-01 → 2026-05-31
PIs
3
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF CALIFORNIA, SAN DIEGO

NIH #3U01DA052769-04S1

Single-cell analysis of aging-associated 4D nucleome in the human hippocampus

Amount
$382K
Period
2020-09-30 → 2025-08-31
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NIH #5U01DA052769-05

Single-Cell Analysis of Aging-Associated 4D Nucleome in the Human Hippocampus

Amount
$595K
Period
2020-09-30 → 2025-08-31
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NIH #5U01DA052769-04

Single-Cell Analysis of Aging-Associated 4D Nucleome in the Human Hippocampus

Amount
$603K
Period
2020-09-30 → 2025-08-31
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NIH #3UM1HG011585-04S1

Center for Integrated Multi-modal and Multi-scale Nucleome Research

Amount
$206K
Period
2020-09-24 → 2025-06-30
PIs
7
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF CALIFORNIA, SAN DIEGO

NIH #5UM1HG011585-05

Center for Integrated Multi-modal and Multi-scale Nucleome Research

Amount
$1.3M
Period
2020-09-24 → 2025-06-30
PIs
7
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF CALIFORNIA, SAN DIEGO

NIH #5UM1HG011585-04

Center for Integrated Multi-modal and Multi-scale Nucleome Research

Amount
$1.3M
Period
2020-09-24 → 2025-06-30
PIs
7
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF CALIFORNIA, SAN DIEGO

NIH #5R01AG066018-05

Epigenome-based Cell Census and Regulatory Element Discovery in the Aging Mouse Brain

Amount
$912K
Period
2019-09-30 → 2025-06-30
PIs
2
Est. capacity / PI
~0 students

Awarded at SALK INSTITUTE FOR BIOLOGICAL STUDIES

NIH #5UM1HG011585-03

Center for Integrated Multi-modal and Multi-scale Nucleome Research

Amount
$1.3M
Period
2020-09-24 → 2025-06-30
PIs
7
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF CALIFORNIA, SAN DIEGO

NIH #5R24AG073198-04

Comparative Single-Cell Epigenomic Analysis of AD-like Pathogenesis in Unconventional Animal Models

Amount
$1.2M
Period
2021-09-01 → 2025-05-31
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NIH #5R24AG073198-03

Comparative Single-Cell Epigenomic Analysis of AD-like Pathogenesis in Unconventional Animal Models

Amount
$1.2M
Period
2021-09-01 → 2025-05-31
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NIH #5R01AG067153-05

Epigenomic analysis of neural circuits in Alzheimer's disease mouse models

Amount
$739K
Period
2020-04-15 → 2025-03-31
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NIH #5R01AG067153-04

Epigenomic analysis of neural circuits in Alzheimer's disease mouse models

Amount
$749K
Period
2020-04-15 → 2025-03-31
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NIH #5R01AG067153-03

Epigenomic analysis of neural circuits in Alzheimer's disease mouse models

Amount
$758K
Period
2020-04-15 → 2025-03-31
PIs
3
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NIH #5R41MH128993-02

Broadly Accessible Technologies for Single-cell Joint Analysis of Transcriptome and Epigenome

Amount
$445K
Period
2022-09-01 → 2024-08-31
PIs
1
Est. capacity / PI
~0 students

Awarded at EPIGENOME TECHNOLOGIES, INC.

NIH #1R41MH128993-01

Broadly Accessible Technologies for Single-cell Joint Analysis of Transcriptome and Epigenome

Amount
$450K
Period
2022-09-01 → 2024-08-31
PIs
1
Est. capacity / PI
~0 students

Awarded at EPIGENOME TECHNOLOGIES, INC.

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

Potential Collaborators

Recent Publications

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