Full Professor(heuristic)

Genomics and Chromatin Dynamics · Molecular Biology

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h-index131
i10-index296
Publications536
Citations112,644

Grants

12 total · 4 active

NIH #R01AG082127

Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regions

Active
Amount
$2M–$3M
Period
2023-06-01 → 2028-02-29
PIs
3

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NSF #2403088

Collaborative Research: OAC Core: CropDL - Scheduling and Checkpoint/Restart Support for Deep Learning Applications on HPC Clusters

Active
Amount
$200K–$300K
Period
2024-10-01 → 2027-09-30
PIs
1

Awarded at College of William and Mary

NIH #U54AG079758

Spatial mapping senescent cells across the mouse lifespan by multiplex transcriptomics and epigenomics

Active
Amount
$2M–$3M
Period
2022-08-01 → 2027-07-31
PIs
2

Awarded at SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE

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All Grants

12 total · 4 active

NIH #R01AG082127

Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regions

Active
Amount
$2M–$3M
Period
2023-06-01 → 2028-02-29
PIs
3

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NSF #2403088

Collaborative Research: OAC Core: CropDL - Scheduling and Checkpoint/Restart Support for Deep Learning Applications on HPC Clusters

Active
Amount
$200K–$300K
Period
2024-10-01 → 2027-09-30
PIs
1

Awarded at College of William and Mary

NIH #U54AG079758

Spatial mapping senescent cells across the mouse lifespan by multiplex transcriptomics and epigenomics

Active
Amount
$2M–$3M
Period
2022-08-01 → 2027-07-31
PIs
2

Awarded at SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE

NIH #UM1MH130994

Center for Multiomic Human Brain Cell Atlas

Active
Amount
$25M–$26M
Period
2022-09-01 → 2027-06-30
PIs
5

Awarded at SALK INSTITUTE FOR BIOLOGICAL STUDIES

NIH #R01EY031663

Unraveling the molecular pathology of retinal degeneration through single cell genomics

Amount
$600K–$700K
Period
2021-06-01 → 2026-05-31
PIs
3

Awarded at UNIVERSITY OF CALIFORNIA, SAN DIEGO

NIH #U01HG012059

The impact of genomic variation on environment-induced changes in pancreatic beta cell states

Amount
$1M–$2M
Period
2021-09-07 → 2026-05-31
PIs
4

Awarded at UNIVERSITY OF CALIFORNIA, SAN DIEGO

NIH #U01DA052769

Single-Cell Analysis of Aging-Associated 4D Nucleome in the Human Hippocampus

Amount
$600K–$700K
Period
2020-09-30 → 2025-08-31
PIs
2

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NIH #UM1HG011585

Center for Integrated Multi-modal and Multi-scale Nucleome Research

Amount
$1M–$2M
Period
2020-09-24 → 2025-06-30
PIs
7

Awarded at UNIVERSITY OF CALIFORNIA, SAN DIEGO

NIH #R01AG066018

Epigenome-based Cell Census and Regulatory Element Discovery in the Aging Mouse Brain

Amount
$900K–$1000K
Period
2019-09-30 → 2025-06-30
PIs
2

Awarded at SALK INSTITUTE FOR BIOLOGICAL STUDIES

NIH #R24AG073198

Comparative Single-Cell Epigenomic Analysis of AD-like Pathogenesis in Unconventional Animal Models

Amount
$1M–$2M
Period
2021-09-01 → 2025-05-31
PIs
2

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NIH #R01AG067153

Epigenomic analysis of neural circuits in Alzheimer's disease mouse models

Amount
$700K–$800K
Period
2020-04-15 → 2025-03-31
PIs
3

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NIH #R41MH128993

Broadly Accessible Technologies for Single-cell Joint Analysis of Transcriptome and Epigenome

Amount
$400K–$500K
Period
2022-09-01 → 2024-08-31
PIs
1

Awarded at EPIGENOME TECHNOLOGIES, INC.

Recent Public Signals

  1. New paper: An integrated view of the structure and function of the human 4D nucleome (Nature)2025-12-17
  2. New preprint: Multiscale Spatial Transcriptomic Atlas of Human Basal Ganglia Cell-Type and Cellular Community Organization2025-12-05
  3. New NSF award: Collaborative Research: OAC Core: CropDL - Scheduling and Checkpoint/Restart Support for Deep Learning Applications on HPC Clusters2024-10-01

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Data Freshness

  • Publications as of 2026-07-09
  • Grants as of 2026-09-03

Data may not be current

Find elsewhere

Institution / lab homepage Search on ResearchGate

ORCID: 0000-0002-5435-1127

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