Chad J. Creighton

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Cigarette smoke induces FASN-dependent fatty acid metabolic rewiring to drive bladder cancer progression

  Cancer Letters · 2026-05-05

• Development of a multiplex assay for early detection of pancreatic cancer in high-risk groups

  BMC Cancer · 2026-04-21

• Global impact of germline structural variation on the cancer proteome

  Nature Communications · 2026-04-14

• Osimertinib activates a TGF-β2–dependent secretory program that drives lung adenocarcinoma progression

  Journal of Clinical Investigation · 2025-12-09 · 1 citations

• EMT-induced stem cell and mesenchymal programs can be decoupled via cell division and ESRP1-dependent mechanisms

  iScience · 2025-12-01

• UALCAN Mobile, an app for cancer proteogenomic data analysisPreprint

  Research Square · 2025-11-26

• Targeting FZD6 creates therapeutically actionable vulnerabilities for advanced prostate cancer

  Oncogene · 2025-11-24 · 2 citations

• Genomic and Epigenomic Signatures Can Distinguish Aggressive Chromophobe Renal Cell Carcinoma from Indolent Renal Oncocytic Tumors in Clinical-grade Samples

  European Urology Oncology · 2025-11-05

• Rat somatic genome editing enables ER+ breast cancer modelingPreprint

  Proceedings of the National Academy of Sciences · 2025-09-18

• Germline structural variations involving the pediatric brain tumor transcriptome include disease-relevant and ancestry-related genes

  Acta Neuropathologica Communications · 2025-08-20 · 1 citations

• Pan-cancer, multi-omic correlates of survival transcending tumor lineage across 11,019 patients reveal targets and pathways

  npj Precision Oncology · 2025-07-05 · 5 citations

• Global DNA methylation differences involving germline structural variation impact gene expression in pediatric brain tumors

  Nature Communications · 2025-05-21 · 3 citations

• Methylome-Wide Profiling of Early-Onset Colorectal Cancer in Underrepresented Populations

  International Journal of Cancer Care and Delivery · 2025-04-24

• MammOnc-DB, an integrative breast cancer data analysis platform for target discovery

  npj Breast Cancer · 2025-04-18 · 11 citations

• Dichotomous roles of ACBD3 in NSCLC growth and metastasis

  Oncogene · 2025-04-06 · 1 citations

• Author Correction: Genomic basis for RNA alterations in cancer

  UNC Libraries · 2025-03-13

• Abstract A019: UALCAN Mobile app, an update to the cancer multi-omic data analysis application

  Cancer Research · 2025-03-11 · 1 citations

• Noncanonical Wnt/Ror2 Signaling Regulates Basal Cell Fidelity and Branching Morphogenesis in the Mammary GlandPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-02-25 · 1 citations

• MAGE-A4 induces non–small cell lung cancer and tumor-promoting plasma cell accumulation

  Science Advances · 2025-02-12 · 5 citations

• Biguanides antithetically regulate tumor properties by the dose-dependent mitochondrial reprogramming-driven c-Src pathway

  Cell Reports Medicine · 2025-02-01 · 11 citations