Clifford P. Brangwynne

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Enhanced GPP synthesis by Erg20p-peptide fusions and biomolecular condensates boosts monoterpene production in yeast

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-04-30

• Ribosome biogenesis bottlenecks reveal vulnerabilities in cancer

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-04-21

• Kinase KEY1 controls pyrenoid condensate size throughout the cell cycle by disrupting phase separation interactions

  Nature Cell Biology · 2026-03-17

• Metabolism of Epigenetic Ribonucleosides Leads to Nucleolar Stress and Cytotoxicity

  ACS Chemical Biology · 2026-03-06

• BPS2026 – Condensate-driven chromatin organization via elastocapillary interactions

  Biophysical Journal · 2026-02-01

• Design of de novo nucleolar surface proteins

  Biophysical Journal · 2025-12-03

• Kinase KEY1 controls pyrenoid condensate size throughout the cell cycle by disrupting phase separation interactionsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-10 · 1 citations

• Mechanical regulation and activity of nuclear condensates

  Biophysical Journal · 2025-10-08 · 3 citations

• Aberrant host mRNA partitioning in Ebola virus condensates driven by RNA folding perpetuates species-dependent interferon responsePreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-09-14

• Deep Learning of Functional Perturbations from Condensate Morphology

  Cell · 2025-08-19

• Protocol for the isolation, culture, and transfection of squid primary cells

  STAR Protocols · 2025-08-06 · 2 citations

• Chromatin heterogeneity modulates nuclear condensate dynamics and phase behavior

  Nature Communications · 2025-07-11 · 10 citations

• Mapping and engineering RNA-driven architecture of the multiphase nucleolus

  Nature · 2025-07-02 · 39 citations

• Sequestration of ribosome biogenesis factors in HSV-1 nuclear aggregates revealed by spatially resolved thermal profiling

  Science Advances · 2025-06-27 · 4 citations

• Condensate-driven chromatin organization via elastocapillary interactionsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-06-15 · 5 citations

• Metabolism of epigenetic ribonucleosides leads to nucleolar stress and cytotoxicityPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-06-13

• Micropipette aspiration reveals differential RNA-dependent viscoelasticity of nucleolar subcompartments

  Proceedings of the National Academy of Sciences · 2025-05-28 · 15 citations

• Genome-wide mapping of mesoscale neuronal RNA organization and condensationPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-04-20 · 4 citations

• Principles of metabolic pathway control by biomolecular condensates in cells

  Nature Chemical Engineering · 2025-03-12 · 7 citations

• Squid primary cell culture as a model system and experimental toolPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-01-13 · 1 citations