David A. Ruddy

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Targeting CRTC2 reverses <i>STK11</i> mutant NSCLC tumor resistance to immunotherapy

  Proceedings of the National Academy of Sciences · 2026-04-22

• Abstract PR010: ERK hyperactivation-induced lethality as a therapeutic strategy in RAS-driven tumors

  Cancer Research · 2026-03-05

• Supplementary Tables and Figures from Targeting the IL1β Pathway for Cancer Immunotherapy Remodels the Tumor Microenvironment and Enhances Antitumor Immune Responses

  2025-11-26

• Supplemental Figure S1 from Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance

  2025-11-24

• Supplemental Figure S5 from Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance

  2025-11-24

• Supplemental Figure S6 from Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance

  2025-11-24

• Supplemental Figure S4 from Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance

  2025-11-24

• Supplemental Figure S7 from Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance

  2025-11-24

• Supplemental Figure S2 from Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance

  2025-11-24

• Supplemental Figure and Table Legends from Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance

  2025-11-24

• Supplemental Figure S3 from Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance

  2025-11-24

• Supplemental Figure S8 from Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance

  2025-11-24

• Supplemental Tables 1 - 12 from Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance

  2025-11-24

• Abstract C035: Arrayed CRISPR Screening Reveals EFNA1 as a Non-Cell-Autonomous Essential Gene in Pancreatic Cancer Cells

  Molecular Cancer Therapeutics · 2025-10-22 · 1 citations

• Tumor-driven stromal reprogramming in the pre-metastatic lymph nodePreprint

  F1000Research · 2025-10-07 · 1 citations

• Defensive tolerance drives the reprogramming and dysfunction of infiltrating pathogenic B cells assuring the maintenance of tolerancePreprint

  Research Square · 2025-08-18

• Supplementary Table 1 from Dynamic Evolution of Fibroblasts Revealed by Single-Cell RNA Sequencing of Human Pancreatic Cancer

  2025-05-13

• Supplementary Figure 5 from Dynamic Evolution of Fibroblasts Revealed by Single-Cell RNA Sequencing of Human Pancreatic CancerPreprint

  2025-05-13

• Supplementary Figure 1 from Dynamic Evolution of Fibroblasts Revealed by Single-Cell RNA Sequencing of Human Pancreatic CancerPreprint

  2025-05-13

• Supplementary Figure 4 from Dynamic Evolution of Fibroblasts Revealed by Single-Cell RNA Sequencing of Human Pancreatic CancerPreprint

  2025-05-13