David C. Linehan

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• DeCAF defines clinical fibroblast subtypes and multidimensional tumor-stroma crosstalk shaping prognosis and immunotherapy response

  UNC Libraries · 2026-03-14

• DeCAF defines clinical fibroblast subtypes and multidimensional tumor-stroma crosstalk shaping prognosis and immunotherapy response

  Cell Reports Medicine · 2026-02-01 · 2 citations

• “Strength in Screening”: Improving Malnutrition & Sarcopenia Detection in the Emergency Department

  Age and Ageing · 2025-12-01

• Supplementary Tables TS1 from Neoadjuvant Chemotherapy Is Associated with Altered Immune Cell Infiltration and an Anti-Tumorigenic Microenvironment in Resected Pancreatic Cancer

  2025-11-25

• Supplementary Figures FS1 from Neoadjuvant Chemotherapy Is Associated with Altered Immune Cell Infiltration and an Anti-Tumorigenic Microenvironment in Resected Pancreatic Cancer

  2025-11-25

• Supplementary Data from Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity

  2025-11-24

• Supplementary Data from Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity

  2025-11-24

• Type I Interferons: Unraveling their Role in the Response to Short Course Radiotherapy in Rectal Cancer 3621

  The Journal of Immunology · 2025-11-01

• Opioid Stewardship: Successful, Scalable, and Adaptable Departmental Opioid Reduction Program

  Journal of the American College of Surgeons · 2025-10-06

• Abstract B075: Young- and older-onset pancreatic cancers arise through distinct mechanisms: Insights from genomic and germline analyses

  Cancer Research · 2025-09-28

• Abstract B100: Spatial relationships between tumor subtypes and tumor-promoting CAFs with clinical implications

  Cancer Research · 2025-09-28

• Improving Stereotactic Body Radiation Therapy by Rewiring Immunosuppressive Neutrophils in Murine Pancreatic Ductal Adenocarcinoma

  International Journal of Radiation Oncology*Biology*Physics · 2025-07-02

• Assessment of the National Institutes of Health Salary Cap Gap Reveals the Increasing Financial Burden of Training and Hiring Surgeon-Scientists

  Annals of Surgery · 2025-06-18 · 4 citations

• Blocking LIF and PD-L1 enhances the antitumor efficacy of SBRT in murine PDAC models

  Journal for ImmunoTherapy of Cancer · 2025-05-01 · 7 citations

• Postdocs Focus on Research—Surgeons Provide Patient Care—Reply

  JAMA Surgery · 2025-01-29

• Improving SBRT by re-wiring immunosuppressive neutrophils in murine pancreatic ductal adenocarcinomaPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-01-14

• Local delivery of SBRT and IL-12 to Murine PDAC Tumors Modulates HematopoiesisPreprint

  OncoImmunology · 2025-01-14

• Blockade of LIF and PD-L1 Enhances Chemotherapy in Preclinical PDAC Models

  Cancers · 2025-01-09 · 4 citations

• A Reassessment of the Clinical Utility of ⁶⁸Ga‐DOTATATE PET/CT in Patients With Gastroenteropancreatic Neuroendocrine Tumors

  Journal of Surgical Oncology · 2025-01-05

• Supporting Surgeon-Scientists to Prosper as Researchers

  JAMA Surgery · 2024-10-02 · 3 citations