David U. Gorkin

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• SMARCB1 missense mutants disrupt SWI/SNF complex stability and remodeling activity

  Nature Communications · 2026-04-08

• BAF complexes maintain accessibility at stimulus-responsive chromatin and are required for transcriptional stimulus responses

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-03-21 · 1 citations

• Generation and characterization of a knockout mouse of an enhancer of <i>EBF3</i>

  Biology Open · 2025-10-13 · 1 citations

• Abstract 1783 Investigating a Potential Feedback Loop in the Regulation of Non-canonical BAF Subunits: BICRA and BICRAL

  Journal of Biological Chemistry · 2025-05-01

• Abstract 1722 Loss of the Mendelian disease gene BICRA alters the developmental potential of human iPSCs

  Journal of Biological Chemistry · 2025-05-01 · 1 citations

• Abstract 986: <i>SMARCB1</i> missense mutants destabilize SWI/SNF complex stability and remodeling activity

  Cancer Research · 2025-04-21

• SMARCB1 missense mutants disrupt SWI/SNF complex stability and remodeling activityPreprint

  Research Square · 2025-03-26 · 1 citations

• The spectrum of gene intolerance to variation: Insights from a rare disease cohortPreprint

  medRxiv · 2025-01-29 · 2 citations

• Generation and Characterization of a Knockout Mouse of an Enhancer of <i>EBF3</i>Preprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-01-10 · 1 citations

• Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

  MDC Repository (Max-Delbrueck-Center for Molecular Medicine) · 2024-12-20

• Integrative analysis of the 3D genome and epigenome in mouse embryonic tissues

  Nature Structural & Molecular Biology · 2024-12-16 · 7 citations

• Abstract B028: Deep mutational scanning of SMARCB1 identifies missense mutants that destabilize SWI/SNF complex stability and diminish remodeling activity

  Cancer Research · 2024-09-05

• Common DNA sequence variation influences 3-dimensional conformation of the human genome

  UNC Libraries · 2024-08-27