Dean W. Felsher

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Rewiring c-Myc Transcriptional Activity with an O-GlcNAcylation Targeting Chimera (OGTAC)

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-05-07

• Abstract 4065: EcDNA-borne structural variants drive oncogenic fusion transcript amplification

  Cancer Research · 2026-04-03

• EcDNA-borne structural variants drive oncogenic fusion transcript amplification

  Cell · 2026-01-07 · 4 citations

• Supplementary Figures from MYC Overexpression Drives Immune Evasion in Hepatocellular Carcinoma That Is Reversible through Restoration of Proinflammatory Macrophages

  2025-11-24

• Supplementary Tables from MYC Overexpression Drives Immune Evasion in Hepatocellular Carcinoma That Is Reversible through Restoration of Proinflammatory Macrophages

  2025-11-24

• Sex disparity in survival outcomes of advanced gastric adenocarcinoma

  BJC Reports · 2025-08-29

• Targeting the MYC oncogene with a selective bi-steric mTORC1 inhibitor elicits tumor regression in MYC-driven cancers

  Cell chemical biology · 2025-08-01 · 4 citations

• Association of HER2 amplification or overexpression with overall survival in advanced upper gastrointestinal adenocarcinomas

  BJC Reports · 2025-05-14

• eLife Assessment: The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven murine liver cancer cells

  2025-05-06

• eLife Assessment: The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven murine liver cancer cells

  2025-04-17

• Low-level shRNA Cytotoxicity Can Contribute to MYC-induced Hepatocellular Carcinoma in Adult Mice

  Molecular Therapy · 2025-04-10

• Lactobacillus acidophilus potentiates oncolytic virotherapy through modulating gut microbiota homeostasis in hepatocellular carcinoma

  Nature Communications · 2025-04-07 · 15 citations

• EcDNA-borne PVT1 fusion stabilizes oncogenic mRNAsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-04-03 · 2 citations

• Prognostic and biological divergence of upper gastrointestinal adenocarcinomas.

  Journal of Clinical Oncology · 2025-01-27

• eLife Assessment: The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven murine liver cancer cells

  2025-01-06

• MYC Inactivation Restores Immune Surveillance in a Transgenic Mouse Model of T-Cell Acute Lymphoblastic Lymphoma

  Blood · 2024-11-05

• Spatial analysis reveals targetable macrophage-mediated mechanisms of immune evasion in hepatocellular carcinoma minimal residual disease

  Nature Cancer · 2024-09-20 · 44 citations