Douglas A. Mitchell

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Lantibiotic-producing bacteria impact microbiome resilience and colonization resistance

  Cell Host & Microbe · 2025-12-01 · 1 citations

• Biosynthesis of peptidic thiooxazole metallophores installed by multinuclear nonheme iron enzymesPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-11-18 · 1 citations

• Structure-based discovery and definition of RiPP recognition elements

  mSystems · 2025-11-18 · 3 citations

• Aminoacyl-tRNA Specificity of a Ligase Catalyzing Non-ribosomal Peptide Extension

  Journal of the American Chemical Society · 2025-10-09 · 4 citations

• LassoESM a tailored language model for enhanced lasso peptide property prediction

  Nature Communications · 2025-09-29 · 4 citations

• A Versatile Enzymatic Pathway for Modification of Peptide C-Termini

  ACS Central Science · 2025-09-20 · 8 citations

• Aminoacyl-tRNA specificity of a ligase catalyzing non-ribosomal peptide extensionPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-09-14

• Peptidic Tryptophan Halogenation by a Promiscuous Flavin‐Dependent Enzyme

  Angewandte Chemie International Edition · 2025-08-29 · 8 citations

• Peptidic Tryptophan Halogenation by a Promiscuous Flavin‐Dependent Enzyme

  Angewandte Chemie · 2025-08-29

• A versatile enzymatic pathway for modification of peptide C-terminiPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-07-16

• Lantibiotic-producing bacteria impact microbiome resilience and colonization resistancePreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-05-07 · 2 citations

• BPS2025 - Lasso cyclase functions as a chaperone that mediates peptide folding and binding

  Biophysical Journal · 2025-02-01

• Cell-free synthetic biology for natural product biosynthesis and discovery

  Chemical Society Reviews · 2025-01-01 · 44 citations

• Substrate prediction for RiPP biosynthetic enzymes <i>via</i> masked language modeling and transfer learning

  Digital Discovery · 2024-12-02 · 4 citations

• LassoESM: A tailored language model for enhanced lasso peptide property predictionPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2024-10-29 · 2 citations

• Substrate interactions guide cyclase engineering and lasso peptide diversification

  Nature Chemical Biology · 2024-09-11 · 29 citations

• Advances in lasso peptide discovery, biosynthesis, and function

  Trends in Genetics · 2024-08-31 · 42 citations