Feixiong Cheng

Cleveland Clinic

Full Professor(heuristic)

Bioinformatics and Genomic Networks · Molecular Biology

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h-index94
i10-index219
Publications456
Citations59,603

Grants

17 total · 8 active

NIH #R01AG092462

Mapping proteomic changes of tauopathy in human neurons

Active
Amount
$700K–$800K
Period
2025-06-012030-03-31
PIs
3

Awarded at WEILL MEDICAL COLL OF CORNELL UNIV

NIH #R01AG092591

A Multimodal, Multiscale and Multistage Systems Biology (M3SB) Infrastructure for Precision Medicine in Alzheimer’s Disease and Longevity

Active
Amount
$800K–$900K
Period
2025-06-012030-02-28
PIs
3

Awarded at CLEVELAND CLINIC LERNER COM-CWRU

NIH #R33AG083003

Precision Medicine Digital Twins for Alzheimer’s Target and Drug Discovery and Longevity

Active
Amount
$500K–$600K
Period
2023-08-152028-08-31
PIs
1

Awarded at CLEVELAND CLINIC LERNER COM-CWRU

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All Grants

17 total · 8 active

NIH #R01AG092462

Mapping proteomic changes of tauopathy in human neurons

Active
Amount
$700K–$800K
Period
2025-06-012030-03-31
PIs
3

Awarded at WEILL MEDICAL COLL OF CORNELL UNIV

NIH #R01AG092591

A Multimodal, Multiscale and Multistage Systems Biology (M3SB) Infrastructure for Precision Medicine in Alzheimer’s Disease and Longevity

Active
Amount
$800K–$900K
Period
2025-06-012030-02-28
PIs
3

Awarded at CLEVELAND CLINIC LERNER COM-CWRU

NIH #R33AG083003

Precision Medicine Digital Twins for Alzheimer’s Target and Drug Discovery and Longevity

Active
Amount
$500K–$600K
Period
2023-08-152028-08-31
PIs
1

Awarded at CLEVELAND CLINIC LERNER COM-CWRU

NIH #U01CA294154

Deep learning based 3D network biology knowledge portal for precision oncology

Active
Amount
$400K–$500K
Period
2025-08-042028-07-31
PIs
2

Awarded at CORNELL UNIVERSITY

NIH #R01AG082118

Characterize neuronal and glial cell-specific vulnerability to proteinopathies in Alzheimer's disease using multimodal single-nuclei genomic and epigenomic approaches

Active
Amount
$800K–$900K
Period
2023-09-012028-05-31
PIs
4

Awarded at CLEVELAND CLINIC LERNER COM-CWRU

NIH #R01AG082211

Alzheimer's Disease and Related Dementia-like Sequelae of SARS-CoV-2 Infection: Virus-Host Interactome, Neuropathobiology, and Drug Repurposing

Active
Amount
$700K–$800K
Period
2023-05-152028-04-30
PIs
3

Awarded at CLEVELAND CLINIC LERNER COM-CWRU

NIH #R01AG084250

Microglial Activation and Inflammatory Endophenotypes Underlying Sex Differences of Alzheimer’s Disease

Active
Amount
$500K–$600K
Period
2023-09-222027-05-31
PIs
2

Awarded at CLEVELAND CLINIC LERNER COM-CWRU

NIH #R01AG076448

TREM2 Genotype-Informed Drug Repurposing and Combination Therapy Design for Alzheimer’s Disease

Active
Amount
$800K–$900K
Period
2022-07-152027-03-31
PIs
3

Awarded at CLEVELAND CLINIC LERNER COM-CWRU

NIH #OT2OD038083

HF-ETIOLOGY: Heart Failure Endotypes from Ethical, Multi-Modal AI driven and Molecular/Phenotypic Data Integration Enabled Discovery

Amount
$1M–$2M
Period
2025-09-012026-08-31
PIs
4

Awarded at NORTHWESTERN UNIVERSITY

NIH #U01AG073323

Alzheimer's MultiOme Data Repurposing: Artificial Intelligence, Network Medicine, and Therapeutics Discovery

Amount
$700K–$800K
Period
2021-09-012026-08-31
PIs
3

Awarded at CLEVELAND CLINIC LERNER COM-CWRU

NIH #RF1NS133812

Dark GPCR signaling underlying the Microbiome-Gut-Brain Axis for Alzheimer's Disease and Related Dementia

Amount
$2M–$3M
Period
2023-08-182026-07-31
PIs
3

Awarded at CLEVELAND CLINIC LERNER COM-CWRU

NIH #RF1AG082211

Alzheimer's Disease and Related Dementia-like Sequelae of SARS-CoV-2 Infection: Virus-Host Interactome, Neuropathobiology, and Drug Repurposing

Amount
$2M–$3M
Period
2023-05-152026-04-30
PIs
3

Awarded at CLEVELAND CLINIC LERNER COM-CWRU

NIH #R21AG083003

Precision Medicine Digital Twins for Alzheimer’s Target and Drug Discovery and Longevity

Amount
$400K–$500K
Period
2023-08-152025-08-14
PIs
1

Awarded at CLEVELAND CLINIC LERNER COM-CWRU

NIH #R01AG066707

Endophenotype Network-based Approaches to Prediction and Population-based Validation of in Silico Drug Repurposing for Alzheimer’s Disease

Amount
$700K–$800K
Period
2020-04-152024-12-31
PIs
1

Awarded at CLEVELAND CLINIC LERNER COM-CWRU

NIH #R56AG074001

Multimodal single-cell genomic and epigenomic analyses elucidate Alzheimer’s sexual dimorphism in human immune systems aging

Amount
$1M–$2M
Period
2021-09-052023-08-31
PIs
4

Awarded at CLEVELAND CLINIC LERNER COM-CWRU

NIH #R00HL138272

An individualized network medicine infrastructure for precision cardio-oncology

Amount
$200K–$300K
Period
2017-07-012021-06-30
PIs
1

Awarded at CLEVELAND CLINIC LERNER COM-CWRU

NIH #K99HL138272

An individualized network medicine infrastructure for precision cardio-oncology

Amount
<$100K
Period
2017-07-012018-06-30
PIs
1

Awarded at NORTHEASTERN UNIVERSITY

Recent Public Signals

  1. New paper: Deep contrastive learning framework identifies cell‐type‐specific drug targets in Alzheimer's disease (Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring)2026-06-29
  2. New preprint: Multi‐View Biomedical Foundation Models for Molecule‐Target and Property Prediction2026-01-28
  3. New NIH award: Deep learning based 3D network biology knowledge portal for precision oncology2025-08-04

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Data Freshness

  • Publications as of 2026-07-09
  • Grants as of 2026-09-03

Data may not be current

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ORCID: 0000-0002-1736-2847

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