Gaorav P. Gupta

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Polθ activity modulates sensitivity to standard therapies in DNMT3A-deficient leukemia

  UNC Libraries · 2026-06-06

• FANCA-dependent FEN1 recruitment suppresses transcription-replication conflicts and PARPi sensitivity

  Molecular Cell · 2026-06-01

• Phase IIa, open-label, multi-center study of the DNA polymerase theta inhibitor ART6043 administered orally in combination with olaparib to patients with HER2-negative breast cancer with a germline BRCA1/2 mutation (randomized expansion of study NCT05898399).

  Journal of Clinical Oncology · 2026-05-28

• The Pathologic Response Evaluation and Detection in Circulating Tumor-DNA Study: Ultrasensitive Circulating Tumor-DNA Assessment of Breast Cancer Minimal Residual Disease

  Journal of Clinical Oncology · 2026-03-10 · 4 citations

• Polθ activity modulates sensitivity to standard therapies in DNMT3A-deficient leukemia

  Cell Reports Medicine · 2026-03-01

• Symptomatic radiation necrosis after concurrent targeted therapy and stereotactic radiosurgery for brain metastases: a bicentric retrospective analysis

  Journal of Neuro-Oncology · 2026-02-01

• Polymerase theta: Genome protection through regulated deployment

  DNA repair · 2025-12-16

• Polymerase θ—what does it see, and why does it matter for cancer therapy?

  UNC Libraries · 2025-11-14

• PARP7 Suppresses Radiation-induced Necroptosis and Abscopal ImmunityPreprint

  Research Square · 2025-11-07

• Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks

  UNC Libraries · 2025-11-05

• Immune profiling of radiation-immunotherapy synergy in an autochthonous breast cancer model 4116

  The Journal of Immunology · 2025-11-01

• Cell composition inference and identification of layer-specific spatial transcriptional profiles with POLARIS

  UNC Libraries · 2025-10-21

• A comprehensive comparison on cell-type composition inference for spatial transcriptomics data

  UNC Libraries · 2025-10-21

• PALB2 and 53BP1 govern post-resection homologous recombination DNA repair

  Molecular Cell · 2025-10-15

• Polymerase θ—what does it see, and why does it matter for cancer therapy?

  NAR Cancer · 2025-10-07 · 2 citations

• Tumor Cell Extrinsic Synaptogyrin 3 Expression as a Diagnostic and Prognostic Biomarker in Head and Neck Cancer

  UNC Libraries · 2025-09-30

• Bridging the gap: ctDNA, genomics, and equity in breast cancer care

  UNC Libraries · 2025-08-28

• Bridging the gap: ctDNA, genomics, and equity in breast cancer care

  npj Breast Cancer · 2025-08-16 · 7 citations

• Corrigendum to “Unveiling cGAS mechanisms: Insights into DNA damage and immune sensing in cancer” [DNA Repair 152 (2025) 103868]

  UNC Libraries · 2025-08-14

• Unveiling cGAS Mechanisms: Insights into DNA Damage and Immune Sensing in Cancer

  UNC Libraries · 2025-08-14