Harrison Brand

Broad Institute

Full Professor(heuristic)

Genomics and Rare Diseases · Genetics

h-index48

i10-index85

Publications158

Citations27,936

Grants

12 total · 6 active

NIH #1R21MH138855-01

A copy number variant discovery pipeline for integrated genome-exome sequencing

Active

Amount: $206K
Period: 2025-09-01 → 2027-08-31
PIs: 1
Est. capacity / PI: ~1 students

Awarded at MASSACHUSETTS GENERAL HOSPITAL

NIH #5R01DE031261-05

Integration of polygenic risk and facial morphometrics to decipher the genetic susceptibility of orofacial clefting

Active

Amount: $755K
Period: 2022-01-01 → 2026-12-31
PIs: 1
Est. capacity / PI: ~1 students

Awarded at MASSACHUSETTS GENERAL HOSPITAL

NIH #5R01DE031261-04

Integration of polygenic risk and facial morphometrics to decipher the genetic susceptibility of orofacial clefting

Active

Amount: $763K
Period: 2022-01-01 → 2026-12-31
PIs: 1
Est. capacity / PI: ~1 students

Awarded at MASSACHUSETTS GENERAL HOSPITAL

Student capacity is a rough estimate from remaining award size, split equally among PIs. Actual funding decisions vary.

Lab Funding Health

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Institution / lab homepage Search on ResearchGate

In-Field Influence

0.0039

PageRank within Genetics co-authorship network

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Admission Signals

New paper: Defining a tandem repeat catalog and variation clusters for genome-wide analyses and population databases (The American Journal of Human Genetics)2026-04-22
New NIH award: $206K — A copy number variant discovery pipeline for integrated genome-exome sequencing2025-09-01
New preprint: Distinguishing syndromic and nonsyndromic cleft palate through analysis of protein-altering de novo variants in 816 trios2025-03-04
New NIH award: $755K — Integration of polygenic risk and facial morphometrics to decipher the genetic susceptibility of orofacial clefting2022-01-01
New NIH award: $763K — Integration of polygenic risk and facial morphometrics to decipher the genetic susceptibility of orofacial clefting2022-01-01
New NIH award: $740K — Integration of polygenic risk and facial morphometrics to decipher the genetic susceptibility of orofacial clefting2022-01-01
New NIH award: $771K — Integration of polygenic risk and facial morphometrics to decipher the genetic susceptibility of orofacial clefting2022-01-01
New NIH award: $796K — Integration of polygenic risk and facial morphometrics to decipher the genetic susceptibility of orofacial clefting2022-01-01

Data Freshness

Publications as of 2026-07-01
Grants as of 2026-06-30

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ORCID: 0000-0002-7901-0812

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

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Recent Publications

Last 2 years · showing 20 of 27

Defining a tandem repeat catalog and variation clusters for genome-wide analyses and population databases
The American Journal of Human Genetics · 2026-04-22 · 2 citations
Deleterious coding variation associated with autism is shared across ancestries
Nature Medicine · 2026-03-30
Data from: Tandem repeat variation shapes immune cell type-specific gene expression
Open MIND · 2026-01-01
Structural and transduction patterns of human-specific polymorphic SVA insertions
Mobile DNA · 2025-11-06 · 1 citations
Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database
Nature Communications · 2025-10-31 · 11 citations
De novo rare EMX2 variants lead to idiopathic hypogonadotropic hypogonadism
Genetics in Medicine · 2025-10-25
Haploinsufficiency of <i>GRHL2</i> is associated with orofacial clefting in humans
Human Molecular Genetics · 2025-10-21
Distinguishing syndromic and nonsyndromic cleft palate through analysis of protein-altering de novo variants in 818 trios
The American Journal of Human Genetics · 2025-10-06 · 3 citations
SUN-162 The Contribution Of Rare Non-coding 5’UTR Variants In The Genetic Architecture Of Isolated Hypogonadotropic Hypogonadism
Journal of the Endocrine Society · 2025-10-01
SHARED AND DISTINCT GENETIC ARCHITECTURES OF AUTISM AND NEUROPSYCHIATRIC DISORDERS
European Neuropsychopharmacology · 2025-10-01
Rare variants in PRKCI cause Van der Woude syndrome and other features of peridermopathy
The American Journal of Human Genetics · 2025-09-02 · 3 citations
Distinguishing syndromic and nonsyndromic cleft palate through analysis of protein-altering de novo variants in 816 triosPreprint
medRxiv · 2025-03-04
Rare variants in PRKCI cause Van der Woude syndrome and other features of peridermopathyPreprint
medRxiv · 2025-01-17 · 1 citations
Rare germline structural variants increase risk for pediatric solid tumors
Science · 2025-01-02 · 18 citations
A new chondrichthyan fossil assemblage from the middle Campanian Cliff House Sandstone at Tsaya Canyon, New Mexico
Abstracts with programs - Geological Society of America · 2025-01-01
A new actinopterygian assemblage from the Upper Campanian Cliff House Sandstone at Tsaya Canyon, New Mexico
Abstracts with programs - Geological Society of America · 2025-01-01
Faunal diversity in Western North America during the Campanian and evidence for provincialism in Laramidian dinosaurs
Abstracts with programs - Geological Society of America · 2025-01-01
Resolution of ring chromosomes, Robertsonian translocations, and complex structural variants from long-read sequencing and telomere-to-telomere assembly
The American Journal of Human Genetics · 2024-11-08 · 23 citations
Tandem repeat variation shapes immune cell type-specific gene expressionPreprint
bioRxiv (Cold Spring Harbor Laboratory) · 2024-11-04 · 11 citations
Defining a tandem repeat catalog and variation clusters for genome-wide analysesPreprint
bioRxiv (Cold Spring Harbor Laboratory) · 2024-10-05 · 13 citations

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Harrison Brand

Grants

A copy number variant discovery pipeline for integrated genome-exome sequencing

Integration of polygenic risk and facial morphometrics to decipher the genetic susceptibility of orofacial clefting

Integration of polygenic risk and facial morphometrics to decipher the genetic susceptibility of orofacial clefting

All Grants

A copy number variant discovery pipeline for integrated genome-exome sequencing

Integration of polygenic risk and facial morphometrics to decipher the genetic susceptibility of orofacial clefting

Integration of polygenic risk and facial morphometrics to decipher the genetic susceptibility of orofacial clefting

Integration of polygenic risk and facial morphometrics to decipher the genetic susceptibility of orofacial clefting

Integration of polygenic risk and facial morphometrics to decipher the genetic susceptibility of orofacial clefting

Integration of polygenic risk and facial morphometrics to decipher the genetic susceptibility of orofacial clefting

Integrative Genomic Applications to Understand the Etiology of Unsolved Craniofacial Anomalies

Integrative Genomic Applications to Understand the Etiology of Unsolved Craniofacial Anomalies

Integrative Genomic Applications to Understand the Etiology of Unsolved Craniofacial Anomalies

Integrative Genomic Applications to Understand the Etiology of Unsolved Craniofacial Anomalies

Integrative Genomic Applications to Understand the Etiology of Unsolved Craniofacial Anomalies

New Computational Methods and Emerging Technologies in Prenatal Genetic Diagnosis

Career Trajectory

Research Cluster Map

Potential Collaborators

Recent Publications