Howard L. McLeod

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Propranolol metabolite and enantiomers affect colorectal cancer development by inhibiting MAPK pathway and downregulating PD-1 expression

  International Immunopharmacology · 2025-12-20

• Validation of a Tissue-Based Predictive RNA Test for Immunotherapy Benefit in NSCLC: the PREDAPT study

  medRxiv · 2025-12-15

• A two-stage genome-wide association study to identify novel genetic loci associated with irAEs in lung cancer patients receiving PD-1/PD-L1 inhibitors

  Cancer Letters · 2025-11-22 · 1 citations

• Genomic Analysis of Germline Variation Associated with Survival of Patients with Colorectal Cancer Treated with Chemotherapy Plus Biologics in CALGB/SWOG 80405 (Alliance)

  UNC Libraries · 2025-11-18

• ADRB2 inhibition suppresses cancer immune evasion by regulating tumor SOX10-PD-L1 axis and T cell function

  Journal for ImmunoTherapy of Cancer · 2025-06-01 · 10 citations

• Optimization of oncology biomarker testing in managed care: Best practices and consensus recommendations from an AMCP Market Insights program

  Journal of Managed Care & Specialty Pharmacy · 2025-05-30 · 3 citations

• Facilitating precision medicine in the community oncology setting: Artificial intelligence clinical decision support and expert consultation combined in a demonstration project.

  Journal of Clinical Oncology · 2025-05-28

• Analysis of data-driven physician engagement and effects on patient recruitment for clinical trial targeting rare gene mutations.

  Journal of Clinical Oncology · 2025-05-28

• Bevacizumab-induced hypertension and proteinuria: a genome-wide study of more than 1000 patients

  UNC Libraries · 2025-05-23

• Correction: Bevacizumab-induced hypertension and proteinuria: a genome-wide study of more than 1000 patients

  UNC Libraries · 2025-05-23

• Causal effects of immune cells on the efficacy and adverse drug reactions of platinum drugs

  Acta Biochimica et Biophysica Sinica · 2025-04-08

• Integrating Pharmacogenomics into the Broader Construct of Genomic Medicine: Efforts by the ClinGen Pharmacogenomics Working Group (PGxWG)

  Clinical Chemistry · 2025-01-01 · 16 citations

• Pharmacogenomics in Oncology—Running Out of Excuses for Slow Adoption

  JAMA Network Open · 2024-12-06 · 2 citations

• Multicenter validation of an RNA-based assay to predict anti-PD-1 disease control in patients with recurrent or metastatic head and neck squamous cell carcinoma: the PREDAPT study

  Journal for ImmunoTherapy of Cancer · 2024-11-01 · 9 citations

• Common variation in a long non-coding RNA gene modulates variation of circulating TGF-β2 levels in metastatic colorectal cancer patients (Alliance)

  UNC Libraries · 2024-10-22