James Brugarolas

Texas Oncology

Full Professor(heuristic)

Renal cell carcinoma treatment · Pulmonary and Respiratory Medicine

Compare more Pulmonary and Respiratory Medicine professors.

h-index65
i10-index162
Publications641
Citations18,469

Grants

6 total · 1 active

NIH #R01CA289885

Leveraging First Mouse Model Reproducing Human Translocation Renal Cell Carcinoma to Investigate Molecular Mechanisms

Active
Amount
$500K–$600K
Period
2026-06-202031-05-31
PIs
1

Awarded at UT SOUTHWESTERN MEDICAL CENTER

NIH #R21CA263264

Dissecting the mechanism of cabozantinib anti-tumor effect in renal cancer

Amount
$200K–$300K
Period
2021-07-022023-12-31
PIs
1

Awarded at UT SOUTHWESTERN MEDICAL CENTER

NIH #P50CA196516

The University of Texas Southwestern Medical Center SPORE in Kidney Cancer

Amount
$2M–$3M
Period
2016-08-012021-07-31
PIs
1

Awarded at UT SOUTHWESTERN MEDICAL CENTER

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All Grants

6 total · 1 active

NIH #R01CA289885

Leveraging First Mouse Model Reproducing Human Translocation Renal Cell Carcinoma to Investigate Molecular Mechanisms

Active
Amount
$500K–$600K
Period
2026-06-202031-05-31
PIs
1

Awarded at UT SOUTHWESTERN MEDICAL CENTER

NIH #R21CA263264

Dissecting the mechanism of cabozantinib anti-tumor effect in renal cancer

Amount
$200K–$300K
Period
2021-07-022023-12-31
PIs
1

Awarded at UT SOUTHWESTERN MEDICAL CENTER

NIH #P50CA196516

The University of Texas Southwestern Medical Center SPORE in Kidney Cancer

Amount
$2M–$3M
Period
2016-08-012021-07-31
PIs
1

Awarded at UT SOUTHWESTERN MEDICAL CENTER

NIH #R01CA175754

Evaluation of the BAP1 tumor suppressor gene in renal cell carcinoma

Amount
$300K–$400K
Period
2013-12-032018-11-30
PIs
1

Awarded at UT SOUTHWESTERN MEDICAL CENTER

NIH #R01CA129387

Regulation of the mTOR Pathway by Hypoxia and the REDD1 Protein

Amount
$300K–$400K
Period
2008-09-222013-07-31
PIs
1

Awarded at UT SOUTHWESTERN MEDICAL CENTER

NIH #K08NS051843

VEGF regulation by the TSC2 tumor suppressor

Amount
$100K–$200K
Period
2005-05-182010-02-28
PIs
1

Awarded at UT SOUTHWESTERN MEDICAL CENTER

Recent Public Signals

  1. New preprint: Clear cell renal cell carcinoma consensus transcriptomic programs reveal converging trajectories towards aggressive disease2026-06-26
  2. New NIH award: Leveraging First Mouse Model Reproducing Human Translocation Renal Cell Carcinoma to Investigate Molecular Mechanisms2026-06-20
  3. New paper: Supplementary Figure 2 from HIF-2–Dependent Regulation of PTHrP and Paraneoplastic Hypercalcemia in Aggressive Clear-Cell Renal Cell Carcinoma2026-06-18

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Data Freshness

  • Publications as of 2026-07-09
  • Grants as of 2026-08-23

Data may not be current

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ORCID: 0000-0002-8575-499X

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