NIH #5U01CA271830-05
The impact of reduction of cellular senescence on age-related epigenetic heterogeneity
- Amount
- $188K
- Period
- 2024-09-01 → 2026-08-31
- PIs
- 2
- Est. capacity / PI
- ~0 students
Awarded at UNIVERSITY OF SOUTHERN CALIFORNIA
Cancer Genomics and Diagnostics · Cancer Research
14 total · 8 active
NIH #5U01CA271830-05
Awarded at UNIVERSITY OF SOUTHERN CALIFORNIA
NIH #7U01CA271830-04
Awarded at UNIVERSITY OF SOUTHERN CALIFORNIA
NIH #5R01CA301643-02
Awarded at UNIVERSITY OF COLORADO DENVER
Student capacity is a rough estimate from remaining award size, split equally among PIs. Actual funding decisions vary.
Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.
Transcriptional heterogeneity predicts and enables clonal selection in ageing haematopoiesisPreprint
Research Square · 2026-06-25
Transcriptional heterogeneity predicts and enables clonal selection in ageing haematopoiesis
Zenodo (CERN European Organization for Nuclear Research) · 2026-05-31
Transcriptional heterogeneity predicts and enables clonal selection in ageing haematopoiesis
Zenodo (CERN European Organization for Nuclear Research) · 2026-05-31
Selection for Function in Early Life: Implications for Early‐Onset Pathologies
Evolutionary Applications · 2026-04-01
Hematopoietic stem cell aging promotes TET2 clonal hematopoiesisPreprint
Research Square · 2026-02-09
Of Barriers and Loops—How Evolution Limits Most Cancer Risks to Older Ages
Cancer Discovery · 2026-01-12
bioRxiv (Cold Spring Harbor Laboratory) · 2025-12-25
Cancer Research · 2025-12-04
Blood · 2025-11-03
U2AF1S34F mutant HSPCs have a fitness advantage in aged and inflamed bone marrow
Blood · 2025-11-03 · 1 citations
Experimental Hematology · 2025-11-01
The Role of Selection for Function in Aging and Chronic Diseases: A Novel Evolutionary Perspective
Aging Cell · 2025-09-05 · 4 citations
Respiratory viral infections awaken metastatic breast cancer cells in lungs
Nature · 2025-07-30 · 55 citations
Modelling the ageing dependence of cancer evolutionary trajectories
Nature reviews. Cancer · 2025-07-10 · 7 citations
Advancing cancer research via comparative oncology
Nature reviews. Cancer · 2025-06-27 · 10 citations
The Nature and Nurture of Carcinogenesis
Cancer Discovery · 2025-06-03 · 1 citations
Abstract LB101: <i>Tet2</i> deficiency mitigates epigenetic aging in clonal hematopoiesis
Cancer Research · 2025-04-25
Abstract 2777: Smoking, clonal evolution, and lung cancer risk
Cancer Research · 2025-04-21
Abstract A014: <i>Tet2</i> deficiency mitigates epigenetic aging in clonal hematopoiesis
Cancer Research · 2025-02-01
Aging and Cancer—Inextricably Linked Across the Lifespan
Aging Cell · 2025-01-21 · 10 citations