Jason D. Buenrostro

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Biological aging and generational shifts in early-onset cancer risk

  Nature Medicine · 2026-06-22

• Refining sequence-to-activity models by increasing model resolution

  Bioinformatics Advances · 2026-05-01

• Transcription factor collaboration enables precise T cell state engineering

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-04-22

• Toward AI-Powered Cancer Etiology Research

  Cancer Discovery · 2026-04-13

• Epigenetic memory of colitis promotes tumour growth

  Nature · 2026-03-25 · 13 citations

• Adrenergic signaling coordinates distant and local responses to amputation in axolotl

  Cell · 2025-10-24 · 5 citations

• scooby: modeling multimodal genomic profiles from DNA sequence at single-cell resolution

  Nature Methods · 2025-10-22 · 13 citations

• Coupling CRISPR scanning with targeted chromatin accessibility profiling using a double-stranded DNA deaminase

  Nature Methods · 2025-09-11 · 3 citations

• Engineered histones reshape chromatin in human cellsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-09-11 · 1 citations

• Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumours

  Nature · 2025-09-10 · 23 citations

• Reprogramming Factors Activate a Non-Canonical Oxidative Resilience Pathway That Can Rejuvenate RPEs and Restore VisionPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-09-01

• The Somatic Mosaicism across Human Tissues Network

  Nature · 2025-07-02 · 42 citations

• Expansion in situ genome sequencing links nuclear abnormalities to aberrant chromatin regulation

  Science · 2025-05-29 · 11 citations

• HBO1 functions as an epigenetic barrier to hepatocyte plasticity and reprogramming during liver injury

  Cell stem cell · 2025-05-21 · 4 citations

• Unified molecular approach for spatial epigenome, transcriptome, and cell lineages

  Proceedings of the National Academy of Sciences · 2025-04-18 · 13 citations

• Invigorating discovery and clinical translation of aging biomarkers

  Nature Aging · 2025-03-31 · 6 citations

• Clonal memory of colitis accumulates and promotes tumor growthPreprint

  Research Square · 2025-03-27

• Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma

  Cancer Cell · 2025-03-06 · 1 citations

• Clonal memory of colitis accumulates and promotes tumor growthPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-02-17

• Multi-scale footprinting

  Zenodo (CERN European Organization for Nuclear Research) · 2025-02-13 · 1 citations