Jay Shendure

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• The proteomic landscape and temporal dynamics of human and mouse gastruloid development

  Nature Cell Biology · 2026-04-24 · 1 citations

• Multi-scale dissection, compaction and derivatization of mammalian developmental enhancers

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-04-21

• Retracing and rewriting the evolutionary trajectories of mammalian developmental enhancers

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-04-21

• Remembrance of inflammations past

  Nature · 2026-03-25 · 1 citations

• A parts list of promoters and gRNA scaffolds for mammalian genome engineering and molecular recording

  Nature Biotechnology · 2025-11-11 · 3 citations

• Large-scale discovery of neural enhancers for cis-regulation therapiesPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-11-05 · 3 citations

• Single-cell, multi-region profiling of the macaque brain across the lifespanPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-11-01

• Multiplex design and discovery of proximity handles for programmable proteome editingPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-13 · 2 citations

• Dual-patterned pluripotent stem cells self-organize into a human embryo model with extended anterior-posterior patterningPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-09-25

• Genetic and epigenetic screens in primary human T cells link candidate causal autoimmune variants to T cell networks

  Nature Genetics · 2025-09-18 · 6 citations

• Multicondition and multimodal temporal profile inference during mouse embryonic development

  Genome Research · 2025-08-14 · 2 citations

• Capture-C MPRA: A high-throughput method to simultaneously characterize promoter interactions and regulatory activityPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-06-14 · 3 citations

• Lineage recording in monoclonal gastruloids reveals heritable modes of early developmentPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-05-24 · 7 citations

• Barcoded monoclonal embryoids are a potential solution to confounding bottlenecks in mosaic organoid screensPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-05-24 · 4 citations

• An Improved, High-Yield Method for Isolating Nuclei from Individual Zebrafish Embryos for Single-Nucleus RNA Sequencing

  Zebrafish · 2025-03-05

• CTCF-mediated insulation and chromatin environment modulate Car5b escape from X inactivation

  BMC Biology · 2025-03-03 · 3 citations

• Cross-species imputation and comparison of single-cell transcriptomic profiles

  Genome biology · 2025-02-26 · 8 citations

• Author response: A molecular proximity sensor based on an engineered, dual-component guide RNA

  2025-02-12

• A molecular proximity sensor based on an engineered, dual-component guide RNA

  eLife · 2025-02-12 · 3 citations

• Combinatorial mapping of E3 ubiquitin ligases to their target substrates

  Molecular Cell · 2025-02-01 · 20 citations