Jef D. Boeke

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Author Correction: Physiology and immunology of a pig-to-human decedent kidney xenotransplant

  Nature · 2026-06-04

• Genome-wide histone humanization in yeast disrupts genome organization, replication, and rDNA stability

  Cell Reports · 2026-06-01

• Improved vector toolkit for genome writing in mammalian cells

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-03-16

• To make biology programmable, we must master its generative grammar

  Molecular Therapy · 2026-02-24

• Ancient co-option of LTR retrotransposons as yeast centromeres

  Nature · 2026-02-18 · 2 citations

• Intrahepatic reporter assay reveals leaky somatic blockade of L1 retrotransposition in mice

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-02-12

• Genome writing and Targeted Delivery of the <i>NKX6-3/ANK1</i> gene cluster and its Type 2 Diabetes GWAS Variants to Human iPSCs

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-01-05

• Retrotransposon Activation in the Aged and Alzheimer’s Disease Brain Examined by Nanopore Long-read DNA Sequencing

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-12-15

• Building synthetic chromosomes one yeast at a time: insights from Sc2.0

  Nature Biotechnology · 2025-12-01 · 9 citations

• Multi-omics analysis of a pig-to-human decedent kidney xenotransplant

  Nature · 2025-11-13 · 18 citations

• Physiology and immunology of a pig-to-human decedent kidney xenotransplant

  Nature · 2025-11-13 · 21 citations

• Enhancer activation from transposable elements in extrachromosomal DNA

  Nature Cell Biology · 2025-10-21 · 12 citations

• Genome writing to dissect consequences of SVA retrotransposon disease X-Linked Dystonia ParkinsonismPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-08 · 2 citations

• Myelin pathology is a key feature of X-linked Dystonia ParkinsonismPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-08 · 1 citations

• Pan-cancer analysis reveals context-dependent roles of LINE-1 ORF1p in immune regulation and copy number alterationsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-05

• Figure 4 from Selective Depletion of Cancer Cells with Extrachromosomal DNA via Lentiviral InfectionPreprint

  2025-08-28

• Figure 5 from Selective Depletion of Cancer Cells with Extrachromosomal DNA via Lentiviral InfectionPreprint

  2025-08-28

• Supplementary Figure S4 from Selective Depletion of Cancer Cells with Extrachromosomal DNA via Lentiviral InfectionPreprint

  2025-08-28

• Figure 1 from Selective Depletion of Cancer Cells with Extrachromosomal DNA via Lentiviral InfectionPreprint

  2025-08-28

• Figure 6 from Selective Depletion of Cancer Cells with Extrachromosomal DNA via Lentiviral InfectionPreprint

  2025-08-28