Jigyasha Timsina

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• GPND‐AI NULISA: A 15‐Protein AI classifier for diagnosis and co‐pathology profiling across neurodegenerative diseases

  Alzheimer s & Dementia · 2026-04-28

• GWAS meta-analysis of cerebrospinal fluid Alzheimer’s biomarkers reveals loci regulating lipids, brain volume and autophagy

  Nature Communications · 2026-04-21

• Deep Plasma Proteomics Reveals Shared and Disease-Specific Molecular Signatures in Alzheimer’s Disease and Frontotemporal Dementia

  medRxiv · 2026-04-16

• Proteogenomics in cerebrospinal fluid and plasma reveals new biological fingerprint of cerebral small vessel disease

  Nature Aging · 2025-11-20 · 2 citations

• High-sensitivity plasma proteomics reveals disease-specific signatures and predictive biomarkers of Alzheimer’s disease phenotypes in a large mixed-dementia cohort

  Molecular Neurodegeneration · 2025-11-17 · 7 citations

• Sex-specific genetic regulation of proteomics in cerebrospinal fluid uncovers genetic causes for sex differences in neurodegenerationPreprint

  medRxiv · 2025-10-31 · 2 citations

• Proteomic polygenic risk scores of age-related plasma protein levels reveal a role for Metalloproteinase inhibitor 2 (TIMP2) in cognitive performance

  Neurobiology of Aging · 2025-10-23 · 2 citations

• Cerebrospinal fluid proteomic signatures in cognitively normal individuals identify distinct clusters linked to neurodegeneration

  Nature Aging · 2025-10-14 · 2 citations

• Author Correction: Shared and disease-specific pathways in frontotemporal dementia and Alzheimer’s and Parkinson’s diseases

  Nature Medicine · 2025-09-02 · 1 citations

• European and African ancestry-specific plasma protein-QTL and metabolite-QTL analyses identify ancestry-specific T2D effector proteins and metabolites

  Nature Communications · 2025-08-11 · 5 citations

• Protein-based Diagnosis and Analysis of Co-pathologies Across Neurodegenerative Diseases: Large-Scale AI-Boosted CSF and Plasma ClassificationPreprint

  Research Square · 2025-07-31

• Early Syndecan-4 Upregulation Predicts Cognitive and Pathological Trajectories in Alzheimer DiseasePreprint

  medRxiv · 2025-07-23 · 1 citations

• Shared and disease-specific pathways in frontotemporal dementia and Alzheimer’s and Parkinson’s diseases

  Nature Medicine · 2025-07-15 · 26 citations

• Disruption of the cerebrospinal fluid–plasma protein balance in cognitive impairment and aging

  Nature Medicine · 2025-07-15 · 23 citations

• Protein-based Diagnosis and Analysis of Co-pathologies Across Neurodegenerative Diseases: Large-Scale AI-Boosted CSF and Plasma ClassificationPreprint

  medRxiv · 2025-07-10 · 1 citations

• High-sensitivity plasma proteomics reveals disease-specific signatures and predictive biomarkers of Alzheimer’s disease phenotypes in a large mixed dementia cohortPreprint

  Research Square · 2025-06-29

• Transferability of European-derived Alzheimer’s disease polygenic risk scores across multiancestry populations

  Nature Genetics · 2025-06-18 · 17 citations

• Novel early‐onset Alzheimer‐associated genes influence risk through dysregulation of glutamate, immune activation, and intracellular signaling pathways

  Alzheimer s & Dementia · 2025-06-01 · 7 citations

• GWAS meta-analysis of CSF Alzheimer's disease biomarkers 18,948 individuals reveal novel loci and genes regulating lipid metabolism, brain volume and autophagyPreprint

  Research Square · 2025-05-21 · 1 citations

• Large-scale plasma proteomic profiling unveils diagnostic biomarkers and pathways for Alzheimer’s disease

  Nature Aging · 2025-05-20 · 27 citations