John Budde

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• GWAS meta-analysis of cerebrospinal fluid Alzheimer’s biomarkers reveals loci regulating lipids, brain volume and autophagy

  Nature Communications · 2026-04-21

• <i>Trans</i> -eQTLs reveal the architecture of human gene regulatory networks

  medRxiv · 2026-02-05

• Blood-Based Circular RNAs Enable Early and Accurate Alzheimer’s Disease DiagnosisPreprint

  Research Square · 2025-12-09

• Identification of genetic modifiers influencing disease risk in autosomal dominant Alzheimer disease mutation carriers

  Alzheimer s & Dementia · 2025-12-01

• Sex-specific genetic regulation of proteomics in cerebrospinal fluid uncovers genetic causes for sex differences in neurodegenerationPreprint

  medRxiv · 2025-10-31 · 2 citations

• Cerebrospinal fluid proteomic signatures in cognitively normal individuals identify distinct clusters linked to neurodegeneration

  Nature Aging · 2025-10-14 · 2 citations

• Trans-eQTL mapping prioritises USP18 as a negative regulator of interferon response at a lupus risk locus

  Nature Communications · 2025-10-02 · 5 citations

• Protein-based Diagnosis and Analysis of Co-pathologies Across Neurodegenerative Diseases: Large-Scale AI-Boosted CSF and Plasma ClassificationPreprint

  Research Square · 2025-07-31

• Protein-based Diagnosis and Analysis of Co-pathologies Across Neurodegenerative Diseases: Large-Scale AI-Boosted CSF and Plasma ClassificationPreprint

  medRxiv · 2025-07-10 · 1 citations

• A Comprehensive Study of Circulating Blood Linear RNA nominates CD55 and DLD as novel causal genes and early-stage biomarkers for Parkinson’s DiseasePreprint

  medRxiv · 2025-06-20 · 1 citations

• Novel early‐onset Alzheimer‐associated genes influence risk through dysregulation of glutamate, immune activation, and intracellular signaling pathways

  Alzheimer s & Dementia · 2025-06-01 · 7 citations

• GWAS meta-analysis of CSF Alzheimer's disease biomarkers 18,948 individuals reveal novel loci and genes regulating lipid metabolism, brain volume and autophagyPreprint

  Research Square · 2025-05-21 · 1 citations

• Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures across the Alzheimer disease continuum

  Neuron · 2025-03-14 · 51 citations

• Sex Differences in Apolipoprotein E and Alzheimer Disease Pathology Across Ancestries

  JAMA Network Open · 2025-03-11 · 21 citations

• Whole-genome sequencing reveals the impact of lipid pathway and <i>APOE</i> genotype on brain amyloidosis

  Human Molecular Genetics · 2025-01-29 · 2 citations

• Multi‐cohort cerebrospinal fluid proteomics identifies robust molecular signatures for asymptomatic and symptomatic Alzheimer’s disease

  Alzheimer s & Dementia · 2024-12-01 · 1 citations

• Identification of genetic risk factors for brain amyloid deposition

  Alzheimer s & Dementia · 2024-12-01

• Benchmarking of a multi‐biomarker low‐volume panel for Alzheimer's disease and related dementia research

  Alzheimer s & Dementia · 2024-11-22 · 31 citations

• Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer’s disease

  Nature Genetics · 2024-11-11 · 65 citations

• Genetic architecture of cerebrospinal fluid and brain metabolite levels and the genetic colocalization of metabolites with human traits

  Nature Genetics · 2024-11-11 · 29 citations