John G. Doench

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Table S5 from Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer

  2026-06-18

• Table S2 from Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer

  2026-06-18

• Table S1 from Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer

  2026-06-18

• Table S3 from Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer

  2026-06-18

• Table S4 from Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer

  2026-06-18

• Discovery of Tcf7 regulators with clonally-resolved CRISPR screens identifies Trim28 as a mediator of CD8 T cell differentiation in tumors

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-06-17

• Head-to-Head CRISPRko CRISPRi Perturb-seq: Aligned, filtered data with guide assignments

  Zenodo (CERN European Organization for Nuclear Research) · 2026-06-16

• Head-to-Head CRISPRko CRISPRi Perturb-seq: Aligned, filtered data with guide assignments

  Zenodo (CERN European Organization for Nuclear Research) · 2026-06-16

• CD164 is an endolysomal host factor for entry of Clade A New World Arenaviruses

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-04-22

• KDM6 Enzymes are the Mechanistic Targets of Mutant IDH that Dictate Replication Stress Sensitivity

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-04-17

• Sialylated CD43 forms a glyco-immune barrier that restrains antileukemic immunity

  Science · 2026-04-09 · 5 citations

• A pooled CRISPR screen reveals genes critical for erythroblast enucleation

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-04-07

• Abstract 632: Dynamic characterization of tumor-microenvironment factors that drive pediatric low-grade gliomas.

  Cancer Research · 2026-04-03

• Balancing off-target and on-target considerations for optimized CRISPR-Cas9 knockout library design

  Cell Genomics · 2026-03-25

• Abstract PR010: Deciphering the mechanistic basis of HIFα paralog target selectivity in kidney cancer

  Cancer Research · 2026-03-13

• Optimized parameters for Cas9 CRISPR interference library design

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-02-26 · 1 citations

• Supplementary Table S1 from <i>(R)</i>-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in <i>IDH</i>-Mutant Cancers

  2025-12-11

• Supplementary Table S4 from <i>(R)</i>-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in <i>IDH</i>-Mutant Cancers

  2025-12-11

• Supplementary Fig. S6 from Addressing Tumor Heterogeneity by Sensitizing Resistant Cancer Cells to T cell–Secreted Cytokines

  2025-12-11

• Supplementary Figure S5 from <i>(R)</i>-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in <i>IDH</i>-Mutant Cancers

  2025-12-11