Joseph J. Loparo

Harvard University

Full Professor(heuristic)

DNA Repair Mechanisms · Molecular Biology

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h-index34
i10-index55
Publications121
Citations7,197

Grants

7 total · 3 active

NIH #R35GM158214

Mechanisms of Error-Prone DNA Repair

Active
Amount
$600K–$700K
Period
2025-08-01 → 2030-06-30
PIs
1

Awarded at HARVARD MEDICAL SCHOOL

NIH #R01AI187524

Structure and dynamics of bacterial cell wall synthases

Active
Amount
$700K–$800K
Period
2024-12-13 → 2029-11-30
PIs
2

Awarded at HARVARD MEDICAL SCHOOL

NIH #R01CA272436

Molecular mechanisms of pathway choice in DNA double strand break repair

Active
Amount
$300K–$400K
Period
2022-06-15 → 2027-05-31
PIs
1

Awarded at HARVARD MEDICAL SCHOOL

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All Grants

7 total · 3 active

NIH #R35GM158214

Mechanisms of Error-Prone DNA Repair

Active
Amount
$600K–$700K
Period
2025-08-01 → 2030-06-30
PIs
1

Awarded at HARVARD MEDICAL SCHOOL

NIH #R01AI187524

Structure and dynamics of bacterial cell wall synthases

Active
Amount
$700K–$800K
Period
2024-12-13 → 2029-11-30
PIs
2

Awarded at HARVARD MEDICAL SCHOOL

NIH #R01CA272436

Molecular mechanisms of pathway choice in DNA double strand break repair

Active
Amount
$300K–$400K
Period
2022-06-15 → 2027-05-31
PIs
1

Awarded at HARVARD MEDICAL SCHOOL

NIH #R01GM115487

Visualizing DNA break repair: single-molecule studies of non-homologous end joining

Amount
$300K–$400K
Period
2015-09-01 → 2025-07-31
PIs
1

Awarded at HARVARD MEDICAL SCHOOL

NIH #R01GM114065

Regulation of translesion synthesis by the bacterial replisome

Amount
$300K–$400K
Period
2015-05-15 → 2025-06-30
PIs
1

Awarded at HARVARD MEDICAL SCHOOL

NIH #R03AI159062

Validating a potential interaction between error-prone polymerases and SSB as a therapeutic target for Mycobacterium tuberculosis

Amount
<$100K
Period
2021-03-08 → 2023-08-31
PIs
1

Awarded at HARVARD MEDICAL SCHOOL

NSF #1148818

Division of Molecular and Cellular Biosciences: Investigator-initiated research projects (MCB)

Amount
$600K–$700K
Period
2012-05-01 → 2017-04-30
PIs
1

Recent Public Signals

  1. New paper: DNA polymerase λ autoinhibition is relieved via Ku interaction during non-homologous end joining (Nucleic Acids Research)2026-01-31
  2. New preprint: Mechanisms of HSV-1 helicase–primase inhibition and replication fork complex assembly2025-12-24
  3. New NIH award: Mechanisms of Error-Prone DNA Repair2025-08-01

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Data Freshness

  • Publications as of 2026-07-09
  • Grants as of 2026-08-25

Data may not be current

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ORCID: 0000-0003-4941-4696

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