M. Madan Babu

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Abstract LB040: Identification of a potent and selective PPIL4 degrader with therapeutic potential from a library of Cereblon modulators

  Cancer Research · 2026-04-17

• Baloxavir alleviates severe disease and viremia in ferrets infected with avian- or bovine-origin influenza A(H5N1) virus

  Science Translational Medicine · 2026-02-18 · 1 citations

• BPS2026 – Comprehensive identification of temperature-sensitive GPCRs that are chaperoned by approved drugs

  Biophysical Journal · 2026-02-01

• Targeting glycerophospholipid biosynthesis overcomes chemoresistance driven by SLFN11 loss in Ewing sarcoma

  Cell Death and Disease · 2026-01-31

• Direct-to-Biology Enabled Molecular Glue Discovery

  Journal of the American Chemical Society · 2025-12-24 · 11 citations

• Proteome-wide computational analyses reveal links between protein condensate formation and RNA biology

  Science Advances · 2025-12-03 · 5 citations

• AlphaSync is an enhanced AlphaFold structure database synchronized with UniProt

  Nature Structural & Molecular Biology · 2025-11-11 · 4 citations

• Artificial intelligence in metabolic research

  Nature Metabolism · 2025-10-02 · 4 citations

• Deep Receptor Scanning Reveals General Sequence Constraints on GPCR BiosynthesisPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-09-21 · 3 citations

• Somatic mtDNA mutations at intermediate levels of heteroplasmy are a source of functional heterogeneity among primary leukemic cells

  Science Advances · 2025-09-10 · 3 citations

• Computational structural optimization enhances IL13Rα2 – B7-H3 tandem CAR T cells to overcome antigen-heterogeneity-mediated tumor escape

  Molecular Therapy · 2025-08-13 · 16 citations

• Early methionine availability attenuates T cell exhaustion

  Nature Immunology · 2025-07-23 · 24 citations

• Direct-to-Biology Enabled Molecular Glue DiscoveryPreprint

  ChemRxiv · 2025-07-07

• Protein Dynamics at Different Timescales Unlock Access to Hidden Post-Translational Modification SitesPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-06-27 · 1 citations

• Flush with insight: Decoding GPCR crosstalk in the spinal defecation center

  Cell chemical biology · 2025-06-01 · 1 citations

• <i>SLFN11</i> Loss-Induced Chemoresistance is Associated with Overexpression of Glycerophospholipid Biosynthesis in Ewing SarcomaPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-05-10

• Chemigenetic kinase biosensors illuminate cell signaling networks

  Nature Biotechnology · 2025-04-28

• Encoding and decoding selectivity and promiscuity in the human chemokine-GPCR interaction network

  Cell · 2025-04-23 · 9 citations

• AlphaSync is an enhanced AlphaFold structure database synchronized with UniProtPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-03-14 · 2 citations

• Proteome-wide computational analyses reveal links between protein condensate formation and RNA biologyPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-03-11 · 1 citations