Mark Gerstein

Yale University

Full Professor(heuristic)

Genomics and Chromatin Dynamics · Molecular Biology

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h-index9
i10-index9
Publications21
Citations1,601

Grants

19 total · 8 active

NIH #R01DA063148

Y-SCORCH 2.0: Further Data Mining and Functional Characterization for Single Cell Opioid Responses in the Context of HIV (SCORCH) Program

Active
Amount
$500K–$600K
Period
2025-07-15 → 2030-03-31
PIs
3

NIH #R01DA063316

Team Science for MultiScale Data Mining and Functional Validation of Single-Cell Opioid Responses in the Context of HIV

Active
Amount
$500K–$600K
Period
2025-07-15 → 2030-03-31
PIs
3

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NIH #R01DA065184

Characterizing genetic effects on molecular phenotypes at the single-cell resolution across brain regions in the context of substance use disorder and HIV

Active
Amount
$2M–$3M
Period
2026-03-01 → 2030-02-28
PIs
3

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All Grants

19 total · 8 active

NIH #R01DA063148

Y-SCORCH 2.0: Further Data Mining and Functional Characterization for Single Cell Opioid Responses in the Context of HIV (SCORCH) Program

Active
Amount
$500K–$600K
Period
2025-07-15 → 2030-03-31
PIs
3

NIH #R01DA063316

Team Science for MultiScale Data Mining and Functional Validation of Single-Cell Opioid Responses in the Context of HIV

Active
Amount
$500K–$600K
Period
2025-07-15 → 2030-03-31
PIs
3

Awarded at UNIVERSITY OF CALIFORNIA-IRVINE

NIH #R01DA065184

Characterizing genetic effects on molecular phenotypes at the single-cell resolution across brain regions in the context of substance use disorder and HIV

Active
Amount
$2M–$3M
Period
2026-03-01 → 2030-02-28
PIs
3

NIH #OT2OD040572

Data science approaches to autism: environmental modulators of the transcriptome and gene-x-environment interactions

Active
Amount
$4M–$5M
Period
2025-09-29 → 2028-09-28
PIs
2

Awarded at UNIVERSITY OF CALIFORNIA LOS ANGELES

NIH #U24MH136793

PsychENCODE Data Analysis and Coordination Center

Active
Amount
$800K–$900K
Period
2024-05-01 → 2028-02-29
PIs
2

Awarded at UNIV OF MASSACHUSETTS MED SCH WORCESTER

NIH #U01HG013840

Computational and Statistical Methods to determine variant effect across cell types and development stages

Active
Amount
$1M–$2M
Period
2024-09-23 → 2027-08-31
PIs
2

NIH #T15LM007056

Biomedical Informatics and Data Science Training at Yale

Active
Amount
$800K–$900K
Period
1987-07-01 → 2027-06-30
PIs
2

NIH #U24HG012012

A Data and Administrative Coordinating Center for the Impact of Genomic Variation on Function Consortium

Active
Amount
$4M–$5M
Period
2021-09-01 → 2027-05-31
PIs
3

Awarded at STANFORD UNIVERSITY

NIH #R21AG087875

Team science approach to integrate machine-learning models and functional genomics to study aging in the context of Alzheimer's disease

Amount
$200K–$300K
Period
2024-09-15 → 2026-06-30
PIs
2

NIH #U24HG012108

Laboratory, Data Analysis, and Coordinating Center (LDACC) for the Developmental Human Genotype-Tissue Expression Project

Amount
$1M–$2M
Period
2021-09-22 → 2026-06-30
PIs
6

NIH #UM1DA051410

The Y-SCORCH Data Generation Center at Yale for Single-Cell Opioid Responses in the Context of HIV

Amount
$3M–$4M
Period
2020-08-01 → 2025-07-31
PIs
3

NIH #R01HG010749

Enhancing open data sharing for functional genomics experiments: Measures to quantify genomic information leakage and file formats for privacy preservation

Amount
$500K–$600K
Period
2020-09-02 → 2025-06-30
PIs
1

NIH #R01DA051906

A Big Data Approach to Identify Epigenetic, Transcriptomic, and Network Dynamics as Immune Dysfunction Drivers Associated with HIV Infection and Substance Use Disorder

Amount
$500K–$600K
Period
2020-07-15 → 2025-05-31
PIs
1

NIH #RF1MH123245

Integrative analysis of genomics and imaging data from the BRAIN Initiative and other public data sources

Amount
$1M–$2M
Period
2021-04-01 → 2025-03-31
PIs
2

NIH #U54DA049098

DATA MANAGEMENT AND RESOURCE REPOSITORY FOR THE exRNA ATLAS PHASE II

Amount
$900K–$1000K
Period
2019-08-15 → 2023-07-31
PIs
3

Awarded at BAYLOR COLLEGE OF MEDICINE

NIH #U01MH116492

1/2 Discovery and validation of neuronal enhancers associated with the development of psychiatric disorders

Amount
$1M–$2M
Period
2018-07-06 → 2023-03-31
PIs
2

Awarded at UNIV OF MASSACHUSETTS MED SCH WORCESTER

NSF #1660648

Collaborative Proposal: ABI Innovation:A Graph Based Approach for the Genome Wide Prediction of Conditionaly Essential Genes

Amount
$1M–$2M
Period
2017-09-15 → 2022-08-31
PIs
1

NIH #U24HG009446

EDAC: ENCODE Data Analysis Center

Amount
$1M–$2M
Period
2021-02-01 → 2022-08-31
PIs
2

Awarded at UNIV OF MASSACHUSETTS MED SCH WORCESTER

NSF #9723182

Development of a Database of Protein Motions and Associated Tools

Amount
$300K–$400K
Period
1997-08-01 → 2001-07-31
PIs
1

Recent Public Signals

  1. New NIH award: Characterizing genetic effects on molecular phenotypes at the single-cell resolution across brain regions in the context of substance use disorder and HIV2026-03-01
  2. New paper: Characterization of gut microbiomes in rural Honduras reveals uncharacterized species and associations with human genetic variation (Cell Reports)2025-12-19
  3. New NIH award: Data science approaches to autism: environmental modulators of the transcriptome and gene-x-environment interactions2025-09-29

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Data Freshness

  • Publications as of 2026-07-09
  • Grants as of 2026-08-31

Data may not be current

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