Michael D. Greicius

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• AlphaGenome identifies a deep intronic variant in a family with PLA2G6-associated neurodegeneration: Closing the diagnostic gap in rare genetic diseases

  medRxiv · 2026-06-18

• APOE*4 risk-modifying genes and drug targets in Alzheimer's disease through cell-type-specific genomic analyses.

  PubMed · 2026-06-01

• Association of Rare <i>APOE</i> Missense Variants R189C and W276C With Risk of Alzheimer Disease

  medRxiv · 2026-05-12

• An <i>APOE</i> *4-Informed Genomic Atlas of the X Chromosome in Alzheimer’s Disease

  medRxiv · 2026-05-06

• Effects of α‐synuclein pathology on synaptic dysfunction and clinical outcomes in normal aging

  Alzheimer s & Dementia · 2026-05-01

• Proteomic Signatures of Protected <i>APOE</i> -ε4 Carriers Reveal Causal Pathways Associated with Delayed Alzheimer’s Disease Onset

  medRxiv · 2026-05-01

• Personalized Feature Statistics: Individual-Level Variant Inference under Genetic Ancestry Continuum

  medRxiv · 2026-04-29

• Sex-aware causal inference assessment of the immune system in complex neurodegenerative diseases

  Brain · 2025-12-23 · 3 citations

• <i>APOE</i> *4 risk‐modifying genes and drug targets in Alzheimer's disease through cell‐type‐specific genomic analysesPreprint

  Alzheimer s & Dementia · 2025-12-04

• <i>APOE</i> *4 and Cell‐Type‐specific Risk‐Modifying Genes in Alzheimer’s Disease

  Alzheimer s & Dementia · 2025-12-01

• X Chromosome Genetic Risk Across Sex, APOE*4, and Pleiotropic Traits Reveals Novel Alzheimer's Disease Mechanisms and Risk Genes

  Alzheimer s & Dementia · 2025-12-01

• Cross‐ancestry prioritization of sex‐specific Alzheimer's disease risk genes through genetics and proteogenomics

  Alzheimer s & Dementia · 2025-12-01

• Non‐synonynous <i>APOE</i> variants association in diverse ancestries

  Alzheimer s & Dementia · 2025-12-01

• Impact of SNP Space on Polygenic Risk Modeling for Alzheimer’s Disease

  Alzheimer s & Dementia · 2025-12-01

• Biomarker‐informed characterization of an <i>ABCA7</i> tandem repeat expansion in a family with early‐onset Alzheimer’s Disease

  Alzheimer s & Dementia · 2025-12-01

• Bumetanide in Patients with Alzheimer's Disease (BumxAD): A Phase IIa Clinical Trial

  Alzheimer s & Dementia · 2025-12-01

• Integrative Genetic, Proteogenomic, and Multi-omics Analyses Reveal Sex-Biased Causal Genes and Drug Targets in Alzheimer’s DiseasePreprint

  medRxiv · 2025-11-02 · 3 citations

• ApoE is Secreted as a Lipid Nanoparticle by Mammalian Cells: Implications for Alzheimer’s Disease Pathogenesis

  Biochemistry · 2025-10-24 · 2 citations

• Long-read genome sequencing and multi-omics in aging and neurodegenerationPreprint

  medRxiv · 2025-10-13 · 2 citations

• Plasma proteomics links brain and immune system aging with healthspan and longevity

  Nature Medicine · 2025-07-09 · 68 citations