Michael F. Clarke

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• BCL11B predetermines a persister state in breast cancer that is reversed by TNFα

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-06-11

• Abstract 5274: Impact of ultra-high dose rate (FLASH) versus conventional radiotherapy on tumor control in wild-type and cGAS-knockout mice

  Cancer Research · 2026-04-03

• Abstract 5266: FLASH radiotherapy maintains tumor control and enables safe re-irradiation while preserving normal tissue in breast cancer PDX models

  Cancer Research · 2026-04-03

• Improved reconstruction of single-cell developmental potential with CytoTRACE 2

  Nature Methods · 2025-10-27 · 58 citations

• Mouse lemur cell atlas informs primate genes, physiology and disease

  Nature · 2025-07-30 · 5 citations

• A molecular cell atlas of mouse lemur, an emerging model primate

  Nature · 2025-07-30 · 9 citations

• Abstract 113: Decoding developmental programs driving tumorigenesis and immunotherapy resistance in triple-negative breast cancer

  Cancer Research · 2025-04-21

• Abstract 1256: BCL11B predetermines an immature drug-resistant cell state in breast cancer that is vulnerable to TNF-α treatment

  Cancer Research · 2025-04-21

• The E2F4 transcriptional repressor is a key mechanistic regulator of colon cancer resistance to <i>irinotecan</i> (CPT-11)Preprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-01-24 · 2 citations

• Identification of USP16 cryo‐EM protein structure and development of a small molecule inhibitor to restore compromised neural stem cell regeneration in a mouse Alzheimer’s model

  Alzheimer s & Dementia · 2024-12-01