Michael T. Hemann

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Live-cell Pick-Seq (LiP-Seq): Interrogating ultra-rare mantle cell lymphoma persistent cells after CART19 therapy

  Blood Advances · 2026-03-19 · 1 citations

• Live-cell pick-seq (LiP-Seq): Interrogating ultra-rare Mantle Cell Lymphoma MRD after CD19-targeted CAR T-cell therapy

  Blood · 2025-11-03

• A functional map of CDK-drug interactions at single amino acid resolutionPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-11-03

• Leveraging platinum-protein interactions to overcome chemoresistance

  Nature Communications · 2025-10-20 · 5 citations

• Systemic tumor-targeting gene drive vectors proactively eliminate drug resistance in solid tumorsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-05

• Sensitization of cancer cells to DNA-damaging agents by expression of the REV1 C-terminal domain: Implications for chemotherapy

  Proceedings of the National Academy of Sciences · 2025-09-10 · 1 citations

• Tumor cell-intrinsic stress states drive sensitivity to CAR T cell-therapy in pancreatic cancerPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-07-29

• Structural Identification of Major Molecular Determinants for Phosphotyrosine Recognition in Tyrosine Kinases Reveals Tumour Promoting and Suppressive FunctionsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-06-11

• Multiplexed <i>in vivo</i> base editing identifies functional gene-variant-context interactionsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-02-26

• FAS-less allogeneic CAR T cells

  Nature Biomedical Engineering · 2024-12-20

• A Multi-Site Break through Cancer Trial: Phase II Study Investigating Dual Inhibition of BCL2 and Menin in AML MRD Using the Combination of Venetoclax and Revumenib (Trial In Progress)

  Blood · 2024-11-05 · 5 citations

• Abstract B039: Elucidating the tumor-driven mechanisms of resistance to immunotherapies in pancreatic cancer through in vivo CRISPR/Cas9 knockout screening

  Cancer Immunology Research · 2024-10-18

• Development of an antigen-based approach to noninvasively image CAR T cells in real time and as a predictive tool

  Science Advances · 2024-09-18 · 13 citations

• Abstract B060: Unveiling resistance mechanisms to CAR T-cell therapy in pancreatic cancer through in vivo CRISPR/Cas9 knockout screening

  Cancer Research · 2024-09-15

• Functional genomics reveals an off-target dependency of drug synergy in gastric cancer therapy

  Gastric Cancer · 2024-07-20 · 4 citations