Michael T. Laub

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Bacterial cell division protein FtsZ complexes with a phage protein to activate bacterial immunity

  Nature Microbiology · 2026-06-12

• Unmasking pathogen traits for chronic colonization in neurogenic bladder

  Cell Reports · 2026-04-22

• DefensePredictor: A machine learning model to discover prokaryotic immune systems

  Science · 2026-04-02 · 4 citations

• A membrane-bound nuclease directly cleaves phage DNA during genome injection

  Nature · 2026-02-25 · 1 citations

• Viral SSB-bound ssDNA activates the bacterial anti-phage defense system DARNA

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-02-23

• Bacterial immune activation via supramolecular assembly with phage triggers

  Nature · 2026-02-04 · 4 citations

• A membrane-bound nuclease directly cleaves phage DNA during genome injectionPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-11-03

• Design of Specific Peptide Inhibitors of Toxin-Antitoxin-Mediated Antiphage Defense

  ACS Synthetic Biology · 2025-10-26

• Emergence of antiphage functions from random sequence libraries reveals mechanisms of gene birth

  Proceedings of the National Academy of Sciences · 2025-10-15 · 4 citations

• Multi-environment deep mutational scanning reveals the distribution of temperature-sensitive variants in a bacterial kinase

  Cell Reports · 2025-10-01 · 1 citations

• Unmasking Pathogen Traits for Chronic Colonization in Neurogenic Bladder PatientsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-08-14

• E. coli prophages encode an arsenal of defense systems to protect against temperate phages

  Cell Host & Microbe · 2025-05-22 · 30 citations

• DefensePredictor: A Machine Learning Model to Discover Novel Prokaryotic Immune SystemsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-01-08 · 22 citations

• eLife Assessment: Fast Evolution of SOS-Independent Multi-Drug Resistance in Bacteria

  2024-11-29

• Anti-viral defence by an mRNA ADP-ribosyltransferase that blocks translation

  Nature · 2024-10-23 · 21 citations

• A bacterial immunity protein directly senses two disparate phage proteins

  Nature · 2024-10-16 · 23 citations

• eLife assessment: A lytic transglycosylase connects bacterial focal adhesion complexes to the peptidoglycan cell wall

  2024-10-01

• eLife Assessment: A lytic transglycosylase connects bacterial focal adhesion complexes to the peptidoglycan cell wall

  2024-09-13

• Principles of bacterial innate immunity against viruses

  Current Opinion in Immunology · 2024-08-01 · 12 citations

• eLife Assessment: A lytic transglycosylase connects bacterial focal adhesion complexes to the peptidoglycan cell wall

  2024-07-16