Michael T. Zimmermann

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• PRMT5 inhibition triggers functional ATM deficiency and sensitizes pancreatic cancer to CHK1 blockade

  Frontiers in Cell and Developmental Biology · 2026-03-11

• Mutant KRAS Heterogeneity Shapes Nuclear Architecture During Pancreatic Cancer Initiation

  Epigenomes · 2026-03-10

• An integrative multitiered computational analysis for better understanding the structure and function of 85 miniproteins

  NAR Genomics and Bioinformatics · 2025-10-07

• A Multi-State Structural Genomics Approach Enables Large-Scale, Mechanistic, and Context-Specific Classification of ABCC6 Genetic Variants Implicated in Calcification DiseasesPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-06-23

• Abstract 2539 Defining the Molecular Heterogeneity and Functional Impact of Pancreatic Cancer-Associated KRAS Mutations

  Journal of Biological Chemistry · 2025-05-01

• An Integrative Multitiered Computational Analysis for Better Understanding the Structure and Function of 85 MiniproteinsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-02-05

• Discovery of a MET-driven monogenic cause of steatotic liver disease

  Hepatology · 2025-01-29 · 4 citations

• Advancing deep variant phenotyping of mitochondrial enzyme complexes for precision medicine in allogeneic hematopoietic stem-cell transplantation

  Transplantation Reports · 2025-01-15

• An Analytical Approach that Combines Knowledge from Germline and Somatic Mutations Enhances Tumor Genomic Reanalyses in Precision Oncology

  Journal of Computational Biology · 2024-12-11

• Emergent properties of the lysine methylome reveal regulatory roles via protein interactions and histone mimicry

  Epigenomics · 2024-12-05 · 1 citations

• Computational Structural Genomics Meets Cryo-EM for the Analyses of Mitochondria-Encoded Enzyme Complexes: A Transformational Approach for Deep Variant Phenotyping in Myelodysplastic Neoplasms

  Blood · 2024-11-05 · 1 citations

• MARK2 variants cause autism spectrum disorder via the downregulation of WNT/β-catenin signaling pathway

  The American Journal of Human Genetics · 2024-10-16 · 17 citations

• Advancing Variant Phenotyping in Myelodysplastic Syndromes via Computational Genomics of Mitochondrial Enzyme ComplexesPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2024-09-08

• Mutant KRAS inhibitors enter the scene of precision therapeutics for pancreatic cancer

  Journal of Gastrointestinal Oncology · 2024-08-01 · 2 citations