Nicholas T. Seyfried

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• SECmeres outperform extracellular vesicles as potential blood RNA biomarkers for Alzheimer’s disease

  Nature Communications · 2026-06-22

• Molecular mechanisms underlying amyloid lowering by aducanumab: differential and comparative effects of sex and IgG reveal the post-treatment disease brain

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-06-21

• Plasma Proteomic Networks Reveal Shared Biology with Brain Linked to Alzheimer’s Disease Pathology

  medRxiv · 2026-06-02

• Behavioral and psychological symptoms of dementia: insights from a multivariate and network-based brain proteome-wide study

  medRxiv · 2026-04-24

• Cell-type-aware transcriptome-wide association studies identify 91 independent risk genes for Alzheimer’s disease dementia

  Communications Biology · 2026-04-22 · 2 citations

• Non-linear associations of amyloid-β with resting-state functional networks and their cognitive relevance in a large community-based cohort of cognitively normal older adultsPreprint

  Alzheimer s Research & Therapy · 2026-03-12 · 1 citations

• Integrated phenotypic and proteomic screening identifies top‐tier Alzheimer's disease therapeutic targets

  Alzheimer s & Dementia · 2025-12-01 · 1 citations

• A Multi-omic Atlas of Human Choroid Plexus in Alzheimer’s DiseasePreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-11-25 · 2 citations

• CSF α-Synuclein Seed Amplification Assays and Alzheimer Disease Biomarkers in Dementia With Lewy Bodies

  Neurology · 2025-11-17 · 3 citations

• Plasma TDP-43 is a potential biomarker for advanced limbic-predominant age-related TDP-43 encephalopathy neuropathologic change

  Molecular Neurodegeneration · 2025-11-14 · 5 citations

• CSF Proteomics and Machine Learning Reveal Distinct Stages Across the Alzheimer’s Disease ContinuumPreprint

  medRxiv · 2025-11-13 · 1 citations

• Proximity Labeling of the Tau Repeat Domain Enriches RNA-Binding Proteins That Are Altered in Alzheimer's Disease and Related Tauopathies

  Molecular & Cellular Proteomics · 2025-11-07 · 3 citations

• Amyloid beta binding partners in the brain tissue of older adults

  Alzheimer s & Dementia · 2025-11-01 · 2 citations

• Identification of Novel Kv1.3 Channel-Interacting Proteins Using Proximity Labelling in T-Cells

  Cellular Physiology and Biochemistry · 2025-10-31 · 3 citations

• Integrative brain omics approach highlights sn-1 lysophosphatidylethanolamine in Alzheimer’s dementia

  Nature Communications · 2025-10-31 · 5 citations

• Cerebrospinal fluid proteomics for predictive assessment of Alzheimer’s Disease riskPreprint

  medRxiv · 2025-10-27 · 1 citations

• Integrated phenotypic and proteomic screening identifies top-tier Alzheimer’s disease therapeutic targetsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-16

• Multi-scale integration of human brain vascular and CSF proteomes reveals biomarkers of cerebral amyloid angiopathy linked to Alzheimer’s disease riskPreprint

  medRxiv · 2025-10-13 · 3 citations

• Brain wide engraftment of human monocytes induces neurodegeneration and cognitive dysfunctionPreprint

  Research Square · 2025-10-10 · 1 citations

• Neuroinflammatory Stress Preferentially Impacts Synaptic MAPK Signaling and Mitochondria in Excitatory NeuronsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-05 · 1 citations