Nicolas Altemose

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Abstract 1930: Unveiling ecDNA spatial organization and epigenetic landscapes through long-read multi-omic sequencing and high-content microscopy.

  Cancer Research · 2026-04-03

• Integrated analysis of multimodal long-read epigenetic assaysPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-11-09

• A telomere-to-telomere map of somatic mutation burden and functional impact in cancerPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-13 · 6 citations

• A complete diploid human genome benchmark for personalized genomicsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-09-21 · 21 citations

• NKX2-1 drives neuroendocrine transdifferentiation of prostate cancer via epigenetic and 3D chromatin remodeling

  Nature Genetics · 2025-07-21 · 23 citations

• Purification and Activity Testing for Nanobody-Hia5 Fusions v1Preprint

  2025-06-17

• DiMeLo-cito: a one-tube protocol for mapping protein-DNA interactions reveals CTCF bookmarking in mitosisPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-03-14 · 9 citations

• Integrating Single-Molecule Sequencing and Deep Learning to Predict Haplotype-Specific 3D Chromatin Organization in a Mendelian ConditionPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-03-02 · 1 citations

• Evolution and instability of human centromeres are accelerated by heterochromatin boundary loss and CENP-A overexpressionPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-02-03 · 9 citations

• Epigenetic remodeling and 3D chromatin reorganization governed by NKX2-1 drive neuroendocrine prostate cancerPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2024-12-07 · 3 citations

• Enhancing transcription–replication conflict targets ecDNA-positive cancers

  Nature · 2024-11-06 · 88 citations

• Human Satellite 3 DNA encodes megabase-scale transcription factor binding platformsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2024-10-23 · 7 citations

• Mapping protein–DNA interactions with DiMeLo-seq

  Nature Protocols · 2024-09-05 · 10 citations