Philip L. De Jager

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Innate immune signaling and functions in astrocytes

  Nature Immunology · 2026-06-29

• Combining post-mortem and neuroimaging measures of brain amyloidosis to accelerate genomic discovery

  Brain · 2026-06-23

• Associations of stable psychological traits with multi-omic subtypes of Alzheimer’s dementia

  Translational Psychiatry · 2026-06-21

• Post-translational modifications in the brain are critical contributors to Alzheimer’s disease neuropathology and cognitive decline

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-06-13

• Integrated genomic analysis and CRISPRi implicates EGFR in Alzheimer’s disease risk

  npj Dementia · 2025-12-16

• Phosphoproteomics unveils the signaling dynamics in neuronal cells stimulated with insulin and insulin-like growth factors

  Cell Communication and Signaling · 2025-12-11 · 2 citations

• Machine Learning-Based Prediction of Cell-type Resolved Brain eQTLs Enhances Discovery of Variants Explaining Alzheimer’s Disease Heritability

  medRxiv · 2025-12-04

• Distributional genetic effects reveal context-dependent molecular regulation in human brain aging and Alzheimer’s diseasePreprint

  Research Square · 2025-12-01

• <i>APOE, ABCA7</i> , and <i>RASGEF1C</i> are associated with earlier onset of amyloid deposition from more than 4000 harmonized positron emission tomography images

  Alzheimer s & Dementia · 2025-12-01

• Neuroimaging-derived brain endophenotypes link molecular mechanisms to Alzheimer’s disease and agingPreprint

  medRxiv · 2025-11-27

• Proteogenomics in cerebrospinal fluid and plasma reveals new biological fingerprint of cerebral small vessel disease

  Nature Aging · 2025-11-20 · 2 citations

• Gene module-trait network analysis uncovers cell type specific systems and genes relevant to Alzheimer's Disease

  Acta Neuropathologica Communications · 2025-11-04

• Sex-specific associations of gene expression with Alzheimer’s disease neuropathology and ante-mortem cognitive performance

  Nature Communications · 2025-10-27 · 6 citations

• INPP5D/SHIP1 regulates endo-lysosomal function and cargo-selective phagocytosis in human microgliaPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-27 · 3 citations

• Genetic correlation analysis identifies <i>TMEM106B, ACE</i> , and <i>ERC2</i> as genetic loci shared between Alzheimer’s disease and primary psychiatric disordersPreprint

  medRxiv · 2025-10-07

• Single-cell nanodroplet processing proteomics pipeline for analysis of human-derived microgliaPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-04

• Cytokine expression profile in the human brain of older adults

  Journal of Neuroinflammation · 2025-10-03 · 4 citations

• The Association Between Age of Menopause and Hysterectomy Status and Alzheimer’s Disease Risk in a Cohort of Older White and Black Women

  Journal of Women s Health · 2025-10-01 · 1 citations

• Mapping disease critical spatially variable gene programs by integrating spatial transcriptomics with human geneticsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-09-25

• Integration of aged brain multi-omics reveals cross-system mechanisms underlying Alzheimer’s disease heterogeneityPreprint

  Cell Reports · 2025-09-23