Ramin Shiekhattar

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Acidic bile salts induce APE1-dependent PRDX2 activation to drive oxaliplatin resistance via ferroptosis inhibition

  Redox Biology · 2026-06-09

• The MLLT3 YEATS domain binds histone marks (H3K9/18/27ac/cr) and ncRNA (7SK), linking transcription and RNA signaling to regulate hematopoiesis

  Cell Reports · 2026-06-01

• Emergence of protein-coding enhancer RNAs in primate evolution

  Trends in Genetics · 2026-06-01

• Abstract 7069: Co-targeting menin and LSD1 dismantles oncogenic programs and restores differentiation in MLL-rearranged acute myeloid leukemia.

  Cancer Research · 2026-04-03

• Transcriptional competence defines the heterochromatin nucleating potential of isolated MSR units

  Nature Communications · 2026-03-20

• Bypass of blocking lesions by RNAPII reveals a novel stress induced by DNA damagePreprint

  Genes & Development · 2026-02-05

• Unbalanced chromatin binding of Polycomb complexes drives neurodevelopmental disorders

  Molecular Cell · 2026-02-01

• Synergistic targeting of KMT2A-rearranged AML with combined LSD1 and menin inhibitors

  Blood · 2025-11-03

• Balancing Activation and Repression: CoREST-p300 Antagonism Controls Retinoic Acid-Driven Differentiation in AMLPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-15

• Co-targeting menin and LSD1 dismantles oncogenic programs and restores differentiation in MLL-rearranged AMLPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-15 · 1 citations

• Integrator 20th anniversary: a molecular machine indispensable in development and disease

  Trends in Molecular Medicine · 2025-10-09 · 4 citations

• Retinoic acid and ascorbate synergize to suppress myeloid leukemia via TET2 activation

  Cell Reports · 2025-10-01 · 1 citations

• The MLLT3 YEATS domain is a dual reader of histone marks (H3K9/18/27ac/cr) and ncRNA (7SK), linking epigenetic and RNA signaling to regulate hematopoiesisPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-09-03

• Integrator promotes the association of TFIID and RNA polymerase II to maintain pluripotency during development

  Molecular Cell · 2025-08-01 · 3 citations

• Enhancing transcriptome mapping with rapid PRO-seq profiling of nascent RNA

  Molecular Cell · 2025-07-24 · 1 citations

• TAF1 is required for fetal but not adult hematopoiesis in mice

  Developmental Cell · 2025-07-16 · 2 citations

• Bypass of Blocking Lesions by RNAPII Impairs the Transcriptional DNA Damage ResponsePreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-04-28

• Fine-tuning of gene expression through the Mettl3-Mettl14-Dnmt1 axis controls ESC differentiation

  Cell · 2025-01-17 · 41 citations

• Retinoic Acid and Ascorbate Synergize to Suppress Myeloid Leukemia via TET2 ActivationPreprint

  SSRN Electronic Journal · 2025-01-01

• Tetrameric INTS6-SOSS1 complex facilitates DNA:RNA hybrid autoregulation at double-strand breaks

  Nucleic Acids Research · 2024-10-08 · 7 citations