Robert A. Holt

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• A gene-editing method generates immunotherapeutic CAR T cells in the body

  Nature · 2026-03-18

• Vitamin D deficiency alters prostate epithelial differentiation and increases prostate cancer aggressiveness in ex vivo and in vivo models

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-02-18

• Self-Multimerization of mRNA LNP-Derived Antigen Improves Antibody Responses

  Vaccines · 2026-01-12

• Identification of novel DNA sequence motifs that modulate transcription in T cells

  BMC Genomics · 2026-01-09

• Comprehensive self-antigen screening to assess cross-reactivity in promiscuous T-cell receptors

  Frontiers in Immunology · 2026-01-05

• Identification of novel DNA sequence motifs that modulate transcription in T cells

  Figshare · 2026-01-01

• Self-Multimerization of mRNA LNP-Derived Antigen Improves Antibody Responses

  Open Collections · 2026-01-01

• Identification of novel DNA sequence motifs that modulate transcription in T cells

  Figshare · 2026-01-01

• Additional file 1 of Identification of novel DNA sequence motifs that modulate transcription in T cells

  Open MIND · 2026-01-01

• Additional file 1 of Identification of novel DNA sequence motifs that modulate transcription in T cells

  Figshare · 2026-01-01

• Vitamin D deficiency alters prostate epithelial differentiation and increases prostate cancer aggressiveness in ex vivo and in vivo modelsPreprint

  SSRN Electronic Journal · 2026-01-01

• A <i>De Novo</i> Algorithm for Allele Reconstruction from Oxford Nanopore Amplicon Reads, with Application to <i>CYP2D6</i>Preprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-11-08

• Why Canada’s next big infrastructure investment should be in biomanufacturingPreprint

  2025-10-21

• Applying principles of vaccine development to oncomicrobial vaccines

  Blood Advances · 2025-10-01

• Self-multimerization of mRNA LNP-derived antigen improves antibody responsesPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-09-15

• BCMA CAR-T Cells Capable of IL-6-Neutralization Bifunctionally Reduce Cytokine Release Syndrome and IL-6-driven Myeloma Growth in Preclinical Models

  Clinical Lymphoma Myeloma & Leukemia · 2025-09-01

• Identification of Novel DNA Sequence Motifs that Modulate Transcription in T cellsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-07-11

• Comprehensive Functional Self-Antigen Screening to Assess Cross-Reactivity in a Promiscuous Engineered T-cell ReceptorPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-05-16 · 1 citations

• Abstract 4738: Androgen regulation of HER3 in prostate cancer differs by duration of treatment

  Cancer Research · 2025-04-21

• Development and first-in-human CAR T therapy against the pathognomonic MiT-fusion driven protein GPNMBPreprint

  medRxiv · 2025-02-27 · 3 citations