Rodolfo Ghirlando

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• High resolution cryo-EM structure of the Pseudomonas aeruginosa OprM multidrug efflux pump provides target for rational inhibitor design

  Journal of Structural Biology X · 2026-06-01

• Structural and functional insights into the Rcs phosphorelay

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-05-09

• Cleavage at the nsp5–nsp6 site of SARS-CoV-2 main protease intermediate precursor is faster from a monomer than a dimer form

  Journal of Biological Chemistry · 2026-03-21

• Structural basis of double-stranded RNA recognition by the J2 monoclonal antibody

  Nature Communications · 2025-12-13 · 7 citations

• Structural details of helix-mediated multimerization of the conserved region of TDP-43 C-terminal domain

  Nature Communications · 2025-11-26 · 12 citations

• Structural insights into Cir-mediated killing by the antimicrobial protein Microcin V

  Communications Biology · 2025-10-09 · 3 citations

• Structural and functional impact of MProG48Y/ΔP168 mutations in SARS-CoV-2 main protease exhibiting resistance to potent inhibitors

  Structural Dynamics · 2025-09-01

• <i>APOE</i> genotypes differentially remodel the astrocytic lipid droplet-associated proteome to shape lipid droplet dynamicsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-08-20 · 4 citations

• Characterization of an unusual SARS-CoV-2 main protease natural variant exhibiting resistance to nirmatrelvir and ensitrelvir

  Communications Biology · 2025-07-17 · 4 citations

• Cryo-EM structures of the E. coli Ton and Tol motor complexes

  Nature Communications · 2025-07-01 · 9 citations

• HIV-1 vif mediates ubiquitination of the proximal protomer in the APOBEC3H dimer to induce degradation

  Nature Communications · 2025-07-01 · 1 citations

• Asymmetric loading of TnsE regulates Tn7 targeting of DNA replication structures

  Nucleic Acids Research · 2025-06-06 · 1 citations

• Specificity and mechanism of the double-stranded RNA-specific J2 monoclonal antibodyPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-05-10 · 6 citations

• Structural Insights into Cir-mediated Killing by the Antimicrobial Protein Microcin VPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-03-10

• Activity of the mammalian DNA transposon piggyBat from Myotis lucifugus is restricted by its own transposon ends

  Nature Communications · 2025-01-07 · 6 citations

• Cryo-EM structures of the <i>E. coli</i> Ton and Tol motor complexesPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2024-10-09 · 4 citations

• Effects of SARS-CoV-2 Main Protease Mutations at Positions L50, E166, and L167 Rendering Resistance to Covalent and Noncovalent Inhibitors

  Journal of Medicinal Chemistry · 2024-10-07 · 10 citations

• Characterization of alternate encounter assemblies of SARS-CoV-2 main protease

  Journal of Biological Chemistry · 2024-08-14 · 10 citations

• Structural basis of tRNA recognition by the widespread OB fold

  Nature Communications · 2024-07-29 · 8 citations

• Structural details of helix-mediated TDP-43 C-terminal domain multimerizationPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2024-07-06 · 17 citations