Roger A. Greenberg

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Mechanism of K63-linked polyubiquitin recognition and cleavage by the BRCA1-A complex

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-06-09

• Identification of highly immunogenic endogenous dsRNAs from cellular MDA5 filaments

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-06-07

• rDNA breaks activate dsRNA pattern recognition through sense-antisense transcription

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-05-28 · 1 citations

• Landscape of reversion alterations in homologous recombination genes reveals evolutionary constraints

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-05-21

• CHAMP1 complex promotes heterochromatin assembly and reduces replication stress

  Proceedings of the National Academy of Sciences · 2026-01-02

• 53BP1 condensates function as bioreactors for NHEJ directed DNA repair and insulators to determine pathway choice

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-12-23 · 1 citations

• Transactions on micronuclear DNA and implications for immune signaling

  Trends in Biochemical Sciences · 2025-11-21 · 5 citations

• Lnk deficiency enhances translesion synthesis to alleviate replication stress and promote hematopoietic stem cell fitness

  Journal of Clinical Investigation · 2025-10-30

• Mechanisms and genomic implications of break-induced replication

  Nature Structural & Molecular Biology · 2025-08-22 · 8 citations

• CHAMP1 Complex Promotes Heterochromatin Assembly and Reduces Replication StressPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-08-05

• A programmed decline in ribosome levels governs human early neurodevelopment

  Nature Cell Biology · 2025-08-01 · 12 citations

• Abstract P2-02-02: CHEMOTHERAPEUTIC TOPOISOMERASE 2 POISONS GENERATE TREX1 RESISTANT DNA FRAGMENTS THAT INDUCE A POTENT cGAS/STING RESPONSE

  Clinical Cancer Research · 2025-06-13

• Abstract 6159: Transcriptional regulation of DNA damage response and associated inflammatory signaling by CDK7 in prostate cancer

  Cancer Research · 2025-04-21

• Targeting CCNE1 amplified ovarian and endometrial cancers by combined inhibition of PKMYT1 and ATR

  Nature Communications · 2025-04-01 · 23 citations

• Molecular glues that inhibit deubiquitylase activity and inflammatory signaling

  Nature Structural & Molecular Biology · 2025-03-17 · 8 citations

• CHAMP1 complex directs heterochromatin assembly and promotes homology-directed DNA repair

  Nature Communications · 2025-02-17 · 8 citations

• Abstract PR010: TRPV1+ sensory innervation as a novel driver of ovarian cancer progression

  Cancer Research · 2024-11-17 · 1 citations

• Mechanisms of Alternative Lengthening of Telomeres

  Cold Spring Harbor Perspectives in Biology · 2024-11-05 · 40 citations

• Crossing the border: Replication fork adducts move to lysosomes for autophagic repair

  Molecular Cell · 2024-10-01

• CHAMP1 complex directs heterochromatin assembly and promotes homology-directed DNA repairPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2024-09-23