Roger E. McLendon

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Abstract 1293: A multimodal AI framework integrating spatial omics and radiomics for recurrence prediction in glioblastoma.

  Cancer Research · 2026-04-03

• SMARCAL1 is a targetable synthetic lethal therapeutic vulnerability in ATRX-deficient gliomas that use alternative lengthening of telomeres

  Neuro-Oncology · 2026-01-09 · 4 citations

• BIOM-72. INTEGRATIVE SINGLE-NUCLEI SPATIAL TRANSCRIPTOMIC PROFILING OF PRIMARY AND RECURRENT HUMAN IDH-WILDTYPE GLIOBLASTOMA REVEALS CELL-SPECIFIC EGFRVIII EXPRESSION AND ANXA1 SIGNALING AXIS

  Neuro-Oncology · 2025-11-01

• BIOM-89. PI3K PATHWAY ALTERATIONS ARE DRIVERS OF PROGRESSION AND PREDICT WORSE OVERALL SURVIVAL IN NEWLY DIAGNOSED MOLECULARLY-DEFINED OLIGODENDROGLIOMA

  Neuro-Oncology · 2025-11-01

• A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8+ infiltration in glioma

  Scientific Reports · 2025-10-23 · 3 citations

• KS03.4.A SPATIAL MULTI-OMIC PROFILING REVEALS DETERMINANTS OF TIL EXPANDABILITY IN HIGH-GRADE GLIOMAS

  Neuro-Oncology · 2025-10-01

• EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis

  Journal of Clinical Investigation · 2025-05-14

• A Spatial Multi-Omic Framework Identifies Gliomas Permissive to TIL ExpansionPreprint

  Research Square · 2025-04-25 · 1 citations

• Ependymal tumors

  2025-04-01

• Spatial and Cellular Architecture of the Glioblastoma Microenvironment Associated with Tumor-Infiltrating Lymphocyte ExpansionPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-03-31 · 1 citations

• A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8+ infiltration in gliomaPreprint

  Research Square · 2025-01-22

• TMIC-45. CYTOMEGALOVIRUS PP65 ANTIGEN EXPRESSION FOLLOWING PP65-SPECIFIC DENDRITIC CELL VACCINATION IN MATCHED PRIMARY AND RECURRENT GLIOBLASTOMA SPECIMENS

  Neuro-Oncology · 2024-11-01

• BIOM-30. NOVEL HISTOLOGIC AND MOLECULAR BIOMARKERS FOR OLIGODENDROGLIOMA

  Neuro-Oncology · 2024-11-01