Roland L. Dunbrack

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Structural mechanism for noncanonical GPCR signaling in the Hedgehog pathway

  Nature Structural & Molecular Biology · 2026-04-30 · 1 citations

• Supplemental structural files for: 'A Metastatic Melanoma Patient with Rare BRAF V600 Variant Case Report and Protein Modeling Analysis'

  Zenodo (CERN European Organization for Nuclear Research) · 2026-04-21

• Supplemental structural files for: 'A Metastatic Melanoma Patient with Rare BRAF V600 Variant Case Report and Protein Modeling Analysis'

  Zenodo (CERN European Organization for Nuclear Research) · 2026-04-21

• Defining the Active Conformation of Typical Protein Kinase Domains from Substrate-Bound PDB Structures Enables Active-State AlphaFold2 Models for All 437 Human Catalytic Protein Kinases

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-02-19

• Structure-guided analysis and prediction of human E2–E3 ligase pairing specificity

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-02-12 · 1 citations

• BPS2026 – Interfamily crosstalk between ERK2, RSK2, and mTORC2 across four kinase families

  Biophysical Journal · 2026-02-01

• Large-scale structure- and sequence-based comparative analysis enables functional annotation of animal venom peptides

  ChemRxiv · 2025-12-22

• WITHDRAWN

  ChemRxiv · 2025-11-19

• Abstract A029: Mechanistic insight into a germline <i>KDM3C</i> polymorphism associated with chemoradiotherapy outcomes in cancer

  Molecular Cancer Therapeutics · 2025-10-22

• PALB2 and 53BP1 govern post-resection homologous recombination DNA repair

  Molecular Cell · 2025-10-15

• PALB2 and 53BP1 govern post-resection homologous recombination DNA repair

  Molecular Cell · 2025-07-31 · 1 citations

• Better together: Elements of successful scientific software development in a distributed collaborative community

  UNC Libraries · 2025-06-26

• Abstract 7159: Characterizing the role of a <i>KDM3C</i> germline polymorphism in chemoradiotherapy outcomes for rectal and head and neck cancers

  Cancer Research · 2025-04-21

• <i>Rēs ipSAE loquuntur</i> : What’s wrong with AlphaFold’s <i>ipTM</i> score and how to fix itPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-02-14 · 58 citations

• Queer voices in computational biology: the first ISCB LGBTQI+ Symposium

  Bioinformatics Advances · 2024-12-18 · 1 citations

• Impact of primary sequence changes on the self‐association properties of mammalian cystathionine beta‐synthase enzymes

  Protein Science · 2024-11-16 · 1 citations

• A Structural Mechanism for Noncanonical GPCR Signal Transduction in the Hedgehog PathwayPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2024-11-01 · 6 citations

• A renewed call for open artificial intelligence in biomedicinePreprint

  2024-09-16

• Exploring the potential role of palladin in modulating human <scp>CAF</scp> / <scp>ECM</scp> functional units

  Cytoskeleton · 2024-09-06 · 1 citations

• FAM122A ensures cell cycle interphase progression and checkpoint control by inhibiting B55α/PP2A through helical motifs

  Nature Communications · 2024-07-10 · 10 citations