Full Professor(heuristic)

Epigenetics and DNA Methylation · Molecular Biology

h-index93
i10-index212
Publications385
Citations33,649

Grants

50 total · 17 active

NIH #1R01DA065015-01

Single molecule functional validation of neurogenomic alterations in opioid-exposed HIV brain

Active
Amount
$2.4M
Period
2026-02-15 → 2030-01-31
PIs
1
Est. capacity / PI
~35 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #1RF1MH141600-01

Targeting the NLRP3 Inflammasome to Mitigate Neuroinflammation and HIV Persistence in the CNS: Mechanisms and Therapeutic Strategies

Active
Amount
$3.6M
Period
2025-09-22 → 2029-09-21
PIs
3
Est. capacity / PI
~16 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01DA059876-03

Nicotine and NLRP3 Inflammasome in HIV-1-Associated CNS Inflammation

Active
Amount
$759K
Period
2024-05-15 → 2029-02-28
PIs
3
Est. capacity / PI
~2 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

Student capacity is a rough estimate from remaining award size, split equally among PIs. Actual funding decisions vary.

All Grants

50 total · 17 active

NIH #1R01DA065015-01

Single molecule functional validation of neurogenomic alterations in opioid-exposed HIV brain

Active
Amount
$2.4M
Period
2026-02-15 → 2030-01-31
PIs
1
Est. capacity / PI
~35 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #1RF1MH141600-01

Targeting the NLRP3 Inflammasome to Mitigate Neuroinflammation and HIV Persistence in the CNS: Mechanisms and Therapeutic Strategies

Active
Amount
$3.6M
Period
2025-09-22 → 2029-09-21
PIs
3
Est. capacity / PI
~16 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01DA059876-03

Nicotine and NLRP3 Inflammasome in HIV-1-Associated CNS Inflammation

Active
Amount
$759K
Period
2024-05-15 → 2029-02-28
PIs
3
Est. capacity / PI
~2 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01DA059876-02

Nicotine and NLRP3 Inflammasome in HIV-1-Associated CNS Inflammation

Active
Amount
$759K
Period
2024-05-15 → 2029-02-28
PIs
3
Est. capacity / PI
~2 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #1R01DA059876-01

Nicotine and NLRP3 Inflammasome in HIV-1-Associated CNS Inflammation

Active
Amount
$759K
Period
2024-05-15 → 2029-02-28
PIs
3
Est. capacity / PI
~2 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01MH134319-04

Cell-lineage specific epigenomic determinants of HIV latency in humanized mouse brain and blood

Active
Amount
$729K
Period
2023-07-25 → 2028-05-31
PIs
3
Est. capacity / PI
~1 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01MH134319-03

Cell-lineage specific epigenomic determinants of HIV latency in humanized mouse brain and blood

Active
Amount
$729K
Period
2023-07-25 → 2028-05-31
PIs
3
Est. capacity / PI
~1 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01MH134319-02

Cell-lineage specific epigenomic determinants of HIV latency in humanized mouse brain and blood

Active
Amount
$729K
Period
2023-07-25 → 2028-05-31
PIs
3
Est. capacity / PI
~1 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #1R01MH134319-01

Cell-lineage specific epigenomic determinants of HIV latency in humanized mouse brain and blood

Active
Amount
$729K
Period
2023-07-25 → 2028-05-31
PIs
3
Est. capacity / PI
~1 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01DA054526-05

Modeling HIV Microglia-Associated Infection and Inflammation in a Chimeric Mouse Brain

Active
Amount
$750K
Period
2021-08-01 → 2027-05-31
PIs
3
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R33DA048207-05

CELL - AND CIRCUIT - SPECIFIC EXPLORATION OF HIV NEUROGENOMICS IN CONTEXT OF OPIATE AND COCAINE ABUSE

Active
Amount
$664K
Period
2019-06-01 → 2027-03-31
PIs
2
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5U01DA053600-05

Single nuclei transcriptome profiling in addiction circuitry of the HIV+ brain

Active
Amount
$794K
Period
2021-04-01 → 2027-02-28
PIs
2
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5DP1DA056018-05

Single Chromatin Fiber Sequencing and Longitudinal Epigenomic Profiling in HIV+ Brain Cells Exposed to Narcotic and Stimulant

Active
Amount
$1.2M
Period
2022-04-01 → 2027-02-28
PIs
1
Est. capacity / PI
~2 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5DP1DA056018-04

Single Chromatin Fiber Sequencing and Longitudinal Epigenomic Profiling in HIV+ Brain Cells Exposed to Narcotic and Stimulant

Active
Amount
$1.2M
Period
2022-04-01 → 2027-02-28
PIs
1
Est. capacity / PI
~2 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #1DP1DA056018-01

Single Chromatin Fiber Sequencing and Longitudinal Epigenomic Profiling in HIV+ Brain Cells Exposed to Narcotic and Stimulant

Active
Amount
$1.2M
Period
2022-04-01 → 2027-02-28
PIs
1
Est. capacity / PI
~2 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5DP1DA056018-03

Single Chromatin Fiber Sequencing and Longitudinal Epigenomic Profiling in HIV+ Brain Cells Exposed to Narcotic and Stimulant

Active
Amount
$1.2M
Period
2022-04-01 → 2027-02-28
PIs
1
Est. capacity / PI
~2 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5DP1DA056018-02

Single Chromatin Fiber Sequencing and Longitudinal Epigenomic Profiling in HIV+ Brain Cells Exposed to Narcotic and Stimulant

Active
Amount
$1.2M
Period
2022-04-01 → 2027-02-28
PIs
1
Est. capacity / PI
~2 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #1R01DA054526-01

Modeling HIV Microglia-Associated Infection and Inflammation in a Chimeric Mouse Brain

Amount
$744K
Period
2021-08-01 → 2026-05-31
PIs
3
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01DA054526-04

Modeling HIV Microglia-Associated Infection and Inflammation in a Chimeric Mouse Brain

Amount
$767K
Period
2021-08-01 → 2026-05-31
PIs
3
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01DA054526-02

Modeling HIV Microglia-Associated Infection and Inflammation in a Chimeric Mouse Brain

Amount
$744K
Period
2021-08-01 → 2026-05-31
PIs
3
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01DA054526-03

Modeling HIV Microglia-Associated Infection and Inflammation in a Chimeric Mouse Brain

Amount
$744K
Period
2021-08-01 → 2026-05-31
PIs
3
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5U01DA053600-04

Single nuclei transcriptome profiling in addiction circuitry of the HIV+ brain

Amount
$963K
Period
2021-04-01 → 2026-02-28
PIs
2
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #3U01DA053600-03S1

Single nuclei transcriptome profiling in addiction circuitry of the HIV+ brain

Amount
$169K
Period
2021-04-01 → 2026-02-28
PIs
2
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5U01DA053600-02

Single nuclei transcriptome profiling in addiction circuitry of the HIV+ brain

Amount
$794K
Period
2021-04-01 → 2026-02-28
PIs
2
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #1U01DA053600-01

Single nuclei transcriptome profiling in addiction circuitry of the HIV+ brain

Amount
$796K
Period
2021-04-01 → 2026-02-28
PIs
2
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5U01DA053600-03

Single nuclei transcriptome profiling in addiction circuitry of the HIV+ brain

Amount
$794K
Period
2021-04-01 → 2026-02-28
PIs
2
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01MH106056-09

Higher Order Chromatin and Genetic Risk for Schizophrenia

Amount
$816K
Period
2015-01-15 → 2025-07-31
PIs
2
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #4R33DA048207-04

CELL - AND CIRCUIT - SPECIFIC EXPLORATION OF HIV NEUROGENOMICS IN CONTEXT OF OPIATE AND COCAINE ABUSE

Amount
$664K
Period
2019-06-01 → 2025-03-31
PIs
2
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5U01DA048279-05

Functional genomic resource and integrative model of dopaminergic circuitry associated with psychiatric disease

Amount
$660K
Period
2019-05-01 → 2025-02-28
PIs
4
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01MH106056-07

Higher Order Chromatin and Genetic Risk for Schizophrenia

Amount
$816K
Period
2015-01-15 → 2024-07-31
PIs
2
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01MH106056-06

Higher Order Chromatin and Genetic Risk for Schizophrenia

Amount
$859K
Period
2015-01-15 → 2024-07-31
PIs
2
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01MH106056-08

Higher Order Chromatin and Genetic Risk for Schizophrenia

Amount
$816K
Period
2015-01-15 → 2024-07-31
PIs
2
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01DA047880-05

TRANSCRIPTOME AND EPIGENOME MAPPING IN DOPAMINE NEURONS FROM THE OPIOID EXPOSED HUMAN BRAIN

Amount
$661K
Period
2019-09-15 → 2024-06-30
PIs
4
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01DA047880-03

TRANSCRIPTOME AND EPIGENOME MAPPING IN DOPAMINE NEURONS FROM THE OPIOID EXPOSED HUMAN BRAIN

Amount
$659K
Period
2019-09-15 → 2024-06-30
PIs
4
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01DA047880-04

TRANSCRIPTOME AND EPIGENOME MAPPING IN DOPAMINE NEURONS FROM THE OPIOID EXPOSED HUMAN BRAIN

Amount
$659K
Period
2019-09-15 → 2024-06-30
PIs
4
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5U01MH116442-05

The 3D genome in transcriptional regulation across the postnatal life span, with implications for schizophrenia and bipolar disorder

Amount
$1.2M
Period
2018-09-01 → 2024-05-31
PIs
4
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #3U01DA048279-03S1

Functional genomic resource and integrative model of dopaminergic circuitry associated with psychiatric disease

Amount
$15K
Period
2019-05-01 → 2024-02-29
PIs
4
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5U01DA048279-03

Functional genomic resource and integrative model of dopaminergic circuitry associated with psychiatric disease

Amount
$722K
Period
2019-05-01 → 2024-02-29
PIs
4
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5U01DA048279-02

Functional genomic resource and integrative model of dopaminergic circuitry associated with psychiatric disease

Amount
$722K
Period
2019-05-01 → 2024-02-29
PIs
4
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5U01DA048279-04

Functional genomic resource and integrative model of dopaminergic circuitry associated with psychiatric disease

Amount
$660K
Period
2019-05-01 → 2024-02-29
PIs
4
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01DA043980-05

(Epi)genetic Risk Architectures in Opioid Dependent Brain

Amount
$746K
Period
2017-09-15 → 2023-05-31
PIs
3
Est. capacity / PI
~0 students

Awarded at CASE WESTERN RESERVE UNIVERSITY

NIH #5U01MH116442-04

The 3D genome in transcriptional regulation across the postnatal life span, with implications for schizophrenia and bipolar disorder

Amount
$1.2M
Period
2018-09-01 → 2023-05-31
PIs
4
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01MH117790-04

Epigenomic Regulation of a Large, Neuron-specific Chromatin Domain

Amount
$412K
Period
2018-07-09 → 2023-05-31
PIs
1
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5U01MH116442-03

The 3D genome in transcriptional regulation across the postnatal life span, with implications for schizophrenia and bipolar disorder

Amount
$1.2M
Period
2018-09-01 → 2023-05-31
PIs
4
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01MH117790-03

Epigenomic Regulation of a Large, Neuron-specific Chromatin Domain

Amount
$412K
Period
2018-07-09 → 2023-05-31
PIs
1
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01MH117790-05

Epigenomic Regulation of a Large, Neuron-specific Chromatin Domain

Amount
$412K
Period
2018-07-09 → 2023-05-31
PIs
1
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R61DA048207-03

CELL - AND CIRCUIT - SPECIFIC EXPLORATION OF HIV NEUROGENOMICS IN CONTEXT OF OPIATE AND COCAINE ABUSE

Amount
$594K
Period
2019-06-01 → 2023-02-28
PIs
2
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R01DA043980-04

(Epi)genetic Risk Architectures in Opioid Dependent Brain

Amount
$756K
Period
2017-09-15 → 2022-05-31
PIs
3
Est. capacity / PI
~0 students

Awarded at CASE WESTERN RESERVE UNIVERSITY

NIH #5P50MH096890-10

Chromosomal Conformations in Mouse Depression Models

Amount
$220K
Period
2012-05-01 → 2022-02-28
PIs
1
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

NIH #5R61DA048207-02

CELL - AND CIRCUIT - SPECIFIC EXPLORATION OF HIV NEUROGENOMICS IN CONTEXT OF OPIATE AND COCAINE ABUSE

Amount
$594K
Period
2019-06-01 → 2022-02-28
PIs
2
Est. capacity / PI
~0 students

Awarded at ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

Potential Collaborators

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