Sean F. Brady

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Mode of action guided metagenomic natural product discovery reveals convergent evolution of a ClpP-targeting motif

  Nature Communications · 2026-04-09

• A 5-hydroxymethylcytosine DNA glycosylase provides defense against T-even bacteriophages

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-02-25

• Prevalence and risk factors for Bovine Herpesvirus Type 1 (BoHV-1) infection in Irish beef herds: results from the National Beef Welfare Scheme 2023

  Irish Veterinary Journal · 2025-09-29

• Bioactive molecules unearthed by terabase-scale long-read sequencing of a soil metagenome

  Nature Biotechnology · 2025-09-12 · 5 citations

• Author response: Oxydifficidin, a potent Neisseria gonorrhoeae antibiotic due to DedA-assisted uptake and ribosomal protein RplL sensitivity

  2025-05-28

• Environmental resistome–guided development of resistance-tolerant antibiotics

  Proceedings of the National Academy of Sciences · 2025-05-19 · 3 citations

• Oxydifficidin, a potent Neisseria gonorrhoeae antibiotic due to DedA-assisted uptake and ribosomal protein RplL sensitivity

  eLife · 2025-05-12 · 3 citations

• A CARF-HAD phosphatase effector provides immunity during the type III-A CRISPR-Cas responsePreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-04-30

• Author response: Oxydifficidin, a potent Neisseria gonorrhoeae antibiotic due to DedA assisted uptake and ribosomal protein RplL sensitivity

  2024-12-04

• Oxydifficidin, a potent Neisseria gonorrhoeae antibiotic due to DedA assisted uptake and ribosomal protein RplL sensitivityPreprint

  eLife · 2024-12-04

• Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma

  Nature · 2024-11-20 · 29 citations

• The CRISPR-associated adenosine deaminase Cad1 converts ATP to ITP to provide antiviral immunity

  Cell · 2024-10-28 · 20 citations

• None: Oxydifficidin, a potent Neisseria gonorrhoeae antibiotic due to DedA assisted uptake and ribosomal protein RplL sensitivity

  2024-08-01

• Oxydifficidin, a potent Neisseria gonorrhoeae antibiotic due to DedA-assisted uptake and ribosomal protein RplL sensitivity

  eLife · 2024-08-01 · 4 citations

• Oxydifficidin, a potent Neisseria gonorrhoeae antibiotic due to DedA assisted uptake and ribosomal protein RplL sensitivityPreprint

  eLife · 2024-08-01