Stephen C.J. Parker

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Efferocytosis-induced metabolic shift in bone macrophages drives lactate production and modulates inflammation and osteoclastogenesis

  Frontiers in Immunology · 2025-11-28

• Combining functional annotation and multi-trait fine-mapping methods improves fine-mapping resolution at glycaemic trait loci

  Human Molecular Genetics · 2025-11-18

• Human and rat skeletal muscle single-nuclei multi-omic integrative analyses nominate causal cell types, regulatory elements, and SNPs for complex traits

  UNC Libraries · 2025-11-08

• Loci for insulin processing and secretion provide insight into type 2 diabetes risk

  UNC Libraries · 2025-11-08

• Adipose tissue eQTL meta-analysis highlights the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits

  UNC Libraries · 2025-11-07

• Accelerating Medicines Partnership in Type 2 Diabetes and Common Metabolic Diseases: Collaborating to Maximize the Value of Genetic and Genomic Data.

  UNC Libraries · 2025-11-07

• Extensive differential gene expression and regulation by sex in human skeletal muscle

  UNC Libraries · 2025-11-07

• CelLink: integrating single-cell multi-omics data with weak feature linkage and imbalanced cell populations

  Nucleic Acids Research · 2025-10-29

• Inverse directions of association of higher physical activity and higher insulin resistance with human skeletal muscle cell typae abundance and fiber-type-level gene expressionPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-28

• Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood

  UNC Libraries · 2025-10-22

• Massively parallel reporter assay reveals promoter-, position-, and strand-specific effects in transcription start sitesPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-14

• Molecular responses in abdominal subcutaneous adipose tissue after a session of endurance exercise: effects of exercise intensity

  The Journal of Physiology · 2025-10-12 · 6 citations

• Skeletal muscle enhancer programming of cardiorespiratory fitnessPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-03

• Skeletal muscle eQTL meta-analysis implicates genes in the genetic architecture of muscular and cardiometabolic traits

  The American Journal of Human Genetics · 2025-09-24

• Genetic integration with cell-specific nucleosome positioning resolves causal relationships underlying chromatin accessibility profilesPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-09-13

• Integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D-associated genes and regulatory signals

  Cell Reports · 2025-07-29 · 7 citations

• 246-OR: Single Nuclei Multiome Sequencing Reveals Subtype-Specific Changes in Oligodendrocytes Imparted by the Metabolic Syndrome

  Diabetes · 2025-06-13

• 2121-LB: PanKbase Integrated Single-Cell Map—A Comprehensive Atlas of Human Pancreatic Islets Unlocking Insights into Type 1 and Type 2 Diabetes

  Diabetes · 2025-06-13 · 2 citations

• 1522-P: Integrating Transcriptome of Human Pancreatic Cells and Spatial Tissue Architecture during Type 1 Diabetes Progression at Single-Cell Resolution

  Diabetes · 2025-06-13

• Extensive differential gene expression and regulation by sex in human skeletal muscle

  Cell Genomics · 2025-06-05 · 13 citations