Steven E. Jacobsen

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• A fungal natural product that inhibits plant cellulose biosynthesis by disrupting cellulose synthase complexes

  Proceedings of the National Academy of Sciences · 2026-06-09

• Multiple approaches for CRISPR-based targeting of DNA methylation to promoters of bacterial and viral susceptibility genes in cassava

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-06-06

• A Fungal Natural Product that Inhibits Plant Cellulose Biosynthesis by disrupting Cellulose Synthase Complexes

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-04-13

• A spontaneous termination mechanism of RNA polymerase V shapes the DNA methylation landscape in plants

  The EMBO Journal · 2026-04-02

• Efficient Transgene‐Free Multiplexed Germline Editing via Viral Delivery of an Engineered <scp>TnpB</scp>

  Plant Biotechnology Journal · 2026-03-17 · 2 citations

• Multiple redundant mechanisms account for the majority of gene silencing downstream of DNA methylation

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-02-10

• Targeting dCas9‐SunTag to a Susceptibility Gene Promoter Is Sufficient for CRISPR Interference

  Plant Direct · 2026-02-01 · 1 citations

• Efficient transgene-free multiplexed germline editing via viral delivery of an engineered TnpB

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-01-23 · 1 citations

• Stepwise DNA unwinding gates TnpB genome-editing activity

  bioRxiv (Cold Spring Harbor Laboratory) · 2026-01-09 · 2 citations

• CDCA7 facilitates MET1-mediated CG DNA methylation maintenance in centromeric heterochromatin via linker histone H1

  Proceedings of the National Academy of Sciences · 2025-12-10

• Structure and evolution-guided design of minimal RNA-guided nucleases

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-12-08

• An antagonistic epigenetic mechanism regulating gene expression in pollen revealed through single-nucleus multiomics

  Nature Communications · 2025-11-27

• Virus-induced transgene- and tissue culture-free heritable genome editing in tomatoPreprint

  Proceedings of the National Academy of Sciences · 2025-11-09 · 2 citations

• CRISPR targeting of H3K4me3 activates gene expression and unlocks centromere-proximal crossover recombination in Arabidopsis

  Nature Communications · 2025-10-31 · 7 citations

• An antagonistic epigenetic mechanism regulating gene expression in pollen revealed through single-nucleus multiomicsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-15

• CDCA7 facilitates MET1-mediated CG DNA methylation maintenance in centromeric heterochromatin via histone H1Preprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-09-22 · 2 citations

• REM transcription factors and GDE1 shape the DNA methylation landscape through the recruitment of RNA polymerase IV transcription complexes

  Nature Cell Biology · 2025-06-27 · 10 citations

• Regulation of MORC-1 is key to the CSR-1–mediated germline gene licensing mechanism in <i>C. elegans</i>

  Science Advances · 2025-06-20

• Viral delivery of an RNA-guided genome editor for transgene-free germline editing in Arabidopsis

  Nature Plants · 2025-04-22 · 75 citations

• Targeting dCas9-SunTag to a susceptibility gene promoter is sufficient for CRISPR interferencePreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-03-13 · 3 citations