Tarjei S. Mikkelsen

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Abstract 5329: High throughput screening strategies in the development of logic gated cell therapies

  Cancer Research · 2023-04-04

• 332 CRISPR/Cas9-based integration of a large and modular cassette into a safe harbor site to improve CAR T cell therapy efficacy and safety

  Regular and Young Investigator Award Abstracts · 2022-11-01 · 2 citations

• Abstract 585: AB-1015, a novel integrated circuit T cells containing an ALPG/MSLN logic gate and FAS/PTPN2 shRNA-miR, demonstrates specific and potent activity against ALPG/MSLN tumors

  Cancer Research · 2022-06-15

• Abstract 2840: Identification of a safe harbor CRISPR-Cas9 integration site for improved cell therapy safety and potency

  Cancer Research · 2022-06-15

• 213 AB-X integrated circuit T cells demonstrate improved potency, expansion, and specificity compared to MSLN CAR T cells

  Regular and Young Investigator Award Abstracts · 2021-11-01

• Progenitor identification and SARS-CoV-2 infection in human distal lung organoids

  UNC Libraries · 2021-05-26

• Integrated pseudotime analysis of human pre-implantation embryo single-cell transcriptomes reveals the dynamics of lineage specification

  Cell stem cell · 2021-05-17 · 227 citations

• A short report on optimization of nucleic acid probes by DNA microarray synthesis and next generation sequencingPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2021-05-04

• Progenitor identification and SARS-CoV-2 infection in human distal lung organoids

  Nature · 2020-11-25 · 420 citations

• Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid culturesPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2020-07-27 · 27 citations

• Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal

  UNC Libraries · 2020-04-18

• Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing

  Nature Biotechnology · 2020-03-30 · 494 citations