Tracy L. Young‐Pearse

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Plasma TDP-43 is a potential biomarker for advanced limbic-predominant age-related TDP-43 encephalopathy neuropathologic change

  Molecular Neurodegeneration · 2025-11-14 · 5 citations

• Amyloid beta binding partners in the brain tissue of older adults

  Alzheimer s & Dementia · 2025-11-01 · 2 citations

• INPP5D/SHIP1 regulates endo-lysosomal function and cargo-selective phagocytosis in human microgliaPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-27 · 3 citations

• Genetic and proteomic analysis identifies BAG3 as an amyloid-responsive regulator of neuronal proteostasis

  Acta Neuropathologica · 2025-10-14 · 1 citations

• BAG3 coordinates astrocytic proteostasis of Alzheimer’s disease-linked proteins via proteasome, autophagy, and retromer complex interactionsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-09-21 · 3 citations

• Cortical Gray Matter Proteins Associated With Cerebral Amyloid Angiopathy in Community-Dwelling Older Adults

  Neurology · 2025-08-22 · 2 citations

• Plasma TDP-43 is a potential biomarker for advanced limbic-predominant age-related TDP-43 encephalopathy neuropathologic changePreprint

  medRxiv · 2025-07-11 · 1 citations

• Astrocyte induction of disease-associated microglia is suppressed by acute exposure to fAD neurons in human iPSC triple cultures

  Cell Reports · 2025-06-01 · 21 citations

• A proteogenomic tool uncovers protein markers for human microglial statesPreprint

  Research Square · 2025-05-02

• CLU alleviates Alzheimer’s disease-relevant processes by modulating astrocyte reactivity and microglia-dependent synaptic density

  Neuron · 2025-05-01 · 35 citations

• A proteogenomic tool uncovers protein markers for human microglial statesPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-04-04 · 2 citations

• PLXNB1 and other signaling drives a pathologic astrocyte state contributing to cognitive decline in Alzheimer’s DiseasePreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-02-25 · 8 citations

• Contributions of Genetic Variation in Astrocytes to Cell and Molecular Mechanisms of Risk and Resilience to Late‐Onset Alzheimer's Disease

  Glia · 2025-02-03 · 18 citations

• Contributions of genetic variation in astrocytes to cell and molecular mechanisms of risk and resilience to late onset Alzheimer’s diseasePreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2024-07-31 · 2 citations